73096-39-6

Usage

Uses

3-(1H-Tetrazol-5-yl)benzoic Acid is a useful reactant in organic synthesis.

InChI:InChI=1/C8H6N4O2/c13-8(14)6-3-1-2-5(4-6)7-9-11-12-10-7/h1-4H,(H,13,14)(H,9,10,11,12)

Upstream product

• 1877-72-1 3-Cyanobenzoic acid 
• 75-36-5 acetyl chloride 
• 16885-79-3 sodium 3-cyanobenzoate 
• 148345-63-5 methyl 3-(1H-tetrazol-5-yl)benzoate 
• 13531-48-1 methyl 3-cyanobenzoate 

Downstream Products

• 1417905-78-2 C₁₅H₁₂FN₅O 
• 1093624-62-4 tert-butyl 4-((2-(2-(3-(1H-tetrazol-5-yl)benzamido)phenyl)thiazolo[5,4-b]pyridin-6-yl)methyl)piperazine-1-carboxylate 

Relevant academic research and scientific papers

A kind of single matrix white rare-earth metal compound and its synthesis and use

The invention relates to a type of single-substrate white light rare earth metal compounds and synthesis and application thereof, in particular to [Ln2(3-tzba)4(OH)2(H2O)6].4H2O and synthesis and application thereof, wherein Ln refers to Sm, Dy; 3-H2tzba

Design and Synthesis of 3-Carbamoylbenzoic Acid Derivatives as Inhibitors of Human Apurinic/Apyrimidinic Endonuclease 1 (APE1)

Apurinic/apyrimidinic (AP) endonuclease 1 (APE1) is a multifaceted protein with an essential role in the base excision repair (BER) pathway. Its implication in tumor development, progression, and resistance has been confirmed in multiple cancers, making it a viable target for intensive investigation. In this work, we designed and synthesized different classes of small-molecule inhibitors of the catalytic endonuclease function of APE1 that contain a 3-carbamoylbenzoic acid scaffold. Further structural modifications were made with the aim of increasing the activity and cytotoxicity of these inhibitors. Several of our compounds were shown to inhibit the catalytic endonuclease function of APE1 with potencies in the low-micromolar range invitro, and therefore represent novel classes of APE1 inhibitors worthy of further development.

Urea derivatives useful as anticancer agents

The present invention relates to compounds of formula I And to pharmaceutically acceptable salts, hydrates and prodrugs thereof, wherein R1, R2, R3, R4, R5, R10, R11, b, m, n, p and v are as defined herein. The invention also relates to pharmaceutical compositions containing the above compounds and methods of treating hyperproliferative disorders in mammals by administering the above compounds.

TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS

This invention relates to compounds of formula (I) wherein R. sup.1, R. sup.2, R 3, R 4 and X are as defined in the application. These compounds are CCK-B receptor antagonists and are useful in the treatment and prevention of central nervous system and gastrointestinal disorders. STR1

SPECTRA AND ELECTRONIC STRUCTURE IN THE EXCITED STATE OF CARBOXY-5-PHENYLTETRAZOLES

Absorption and luminescence spectra of ortho-, meta- and para-carboxy-5-phenyltetrazole in aqueous solutions at room and low temperature were measured.Investigations were carried out in super acidic to super basic media.Three dissociation forms were identified (anion, molecule and cation) and corresponding acid-base equilibrium constants in the ground state were determined spectrophotometrically, and in the first excited singlet state from titration curves.The latter ones for anion-molecule equilibrium are in agreement with those calculated by the Foerster cycle.The formation of a twisted internal charge transfer (TICT) excited state of the anion is discussed.