730961-09-8Relevant articles and documents
Synthesis of Normorphans through an Efficient Intramolecular Carbamoylation of Ketones
Diaba, Fa?za,Montiel, Juan A.,Serban, Georgeta,Bonjoch, Josep
supporting information, p. 3860 - 3863 (2015/08/18)
An unexpected C-C bond cleavage was observed in trichloroacetamide-tethered ketones under amine treatment and exploited to develop a new synthesis of normophans from 4-amidocyclohexanones. The reaction involves an unprecedented intramolecular haloform-typ
Six-membered nitrogen ring formation by radical cyclization of trichloroacetamides with enones. A synthetic entry to cis-perhydroisoquinoline- 3,6-diones
Vila, Xavier,Quirante, Josefina,Paloma, Laura,Bonjoch, Josep
, p. 4661 - 4664 (2007/10/03)
Intramolecular reactions between 1-(carbamoyl)dichloromethyl radicals and enones acting as radical acceptors are reported for the first time. The Bu 3SnH promoted 6-exo reaction of trichloroacetamides with enones, avoiding the 1,5-hydrogen transfer, constitutes a new synthetic entry to cis-perhydoisoquinoline-3,6-diones.