730981-22-3

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 730984-94-8 [2-(3-amino-phenyl)-2-hydroxy-ethyl]-carbamic acid tert-butyl ester 
• 730984-92-6 [2-hydroxy-2-(3-nitro-phenyl)-ethyl]-carbamic acid tert-butyl ester 
• 193761-55-6 (R)-2-bromo-1-(3-nitrophenyl)ethan-1-ol 
• 129894-60-6 (R)-2-Amino-1-(3-nitro-phenyl)-ethanol 
• 2227-64-7 3'-nitro-2-bromoacetophenone 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 730981-25-6 N-[3-(2-amino-1-hydroxy-ethyl)-phenyl]-methanesulfonamide 

Relevant academic research and scientific papers

2,4-Thiazolidinediones as potent and selective human β3 agonists

Methylsulfonamide substituted 2,4-thiazolidinedione 22c is a potent (EC50 = 0.01 μM, IA = 1.19) and selective (more than 110-fold over β1 and β2 agonist activity) β3 agonist. This compound has also been proven to be active and selective in an in vivo mode.