730992-58-2Relevant academic research and scientific papers
Synthesis of enantiomerically pure (R,R)- and (S,S)-1,2-Bis(pentafluorophenyl)ethane-1,2-diamine and evaluation of the pK a value by ab initio calculations
Sakai, Takashi,Korenaga, Toshinobu,Washio, Noriyuki,Nishio, Yuji,Minami, Shinichi,Ema, Tadashi
, p. 1001 - 1008 (2004)
1,2-Bis(pentafluorophenyl)ethane-1,2-diamine (1) was synthesized by the imino pinacol coupling of 4-methoxy-N-(pentafluorobenzylidene)benzylamine using a Zn-Cu couple and p-TsOH·H2O. The optical resolution of (±)-1 by means of chiral HPLC gave
