731002-68-9Relevant academic research and scientific papers
Synthesis of S-alkyl L-homocysteine analogues of glutathione and their kinetic studies with γ-glutamyl transpeptidase
Lherbet, Christian,Gravel, Christian,Keillor, Jeffrey W.
, p. 3451 - 3455 (2004)
A series of S-alkyl L-homocysteine analogues of glutathione was synthesized with varied oxidation state of the sulfur and tested for inhibition of rat kidney γ-glutamyl transpeptidase (GGT). The strong selectivity of the enzyme with respect to the sulfur oxidation state reveals important information for the development of powerful competitive inhibitors.
