73101-73-2Relevant academic research and scientific papers
Syntheses of 2-sulfamoylmethylbenzoxazole derivatives and determination of their anticonvulsant activities
Uno,Kurokawa,Masuda
, p. 2359 - 2361 (1981)
Some 2-sulfamoylmethylbenzoxazole derivatives were synthesized from 2-bromomethylbenzoxazole by reaction with sodium bisulfite, followed by chlorination and amination. Among them, 2-sulfamoylmethylbenzoxazole showed the strongest anticonvulsant activity, which was compared with that of 3-sulfamoylmethyl-1,2-benzisoxazole (I).
Methods for the use of inhibitors of cytosolic phospholipase A2 in the treatment of thrombosis
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Page/Page column 32, (2010/11/29)
This invention provides methods for the use of substituted indole compounds of the general formula: and pharmaceutically acceptable salt forms thereof. The invention provides methods for the use of the compounds in the treating or preventing thrombosis in a mammal, or preventing progression of symptoms of thrombosis.
Methane-sulfonamide derivatives, the preparation thereof and composition comprising the same
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, (2008/06/13)
Methane-sulfonamide derivatives of the formula: STR1 wherein R1 is hydrogen or a halogen atom, R2 and R3 are the same or different and are each hydrogen or a straight or branched alkyl having 1 to 3 carbon atoms, and one of X and Y is a carbon atom and another is a nitrogen atom, provided that the group: --CH2 SO2 NR2 R3 is bonded to the carbon atom of either of X and Y, and an alkali metal salt thereof, and a process for the preparation of said methane-sulfonamide derivatives. Said compounds have an excellent anticonvulsant activity and are useful as anticonvulsants for controlling convulsions and seizures in patients with epilepsy.
