Chemical and Pharmaceutical Bulletin p. 2359 - 2361 (1981)
Update date:2022-08-05
Topics:
Uno
Kurokawa
Masuda
Some 2-sulfamoylmethylbenzoxazole derivatives were synthesized from 2-bromomethylbenzoxazole by reaction with sodium bisulfite, followed by chlorination and amination. Among them, 2-sulfamoylmethylbenzoxazole showed the strongest anticonvulsant activity, which was compared with that of 3-sulfamoylmethyl-1,2-benzisoxazole (I).
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(1979)
