73112-03-5

Upstream product

• 31771-58-1 5-amino-4-methoxycarbonyl-1-phenyl-1,2,3-triazole 
• 73112-02-4 3-phenyl-3H-[1,2,3]triazolo-[4,5-d]pyrimidine 
• 151-50-8 potassium cyanide 
• 98-88-4 benzoyl chloride 
• 622-37-7 Phenyl azide 

Downstream Products

• 123888-57-3 1-(p-Chlorophenyl)-4-(N-phenyl)amidino-1,2,3-triazole 
• 123888-50-6 5-Amino-4-(N-p-methoxyphenyl)iminomethyl-1-phenyl-1,2,3-triazole 
• 123888-56-2 1-(p-Methoxyphenyl)-4-(N-phenyl)amidino-1,2,3-triazole 
• 123888-48-2 1-Ethyl-4-(N-phenyl)amidino-1,2,3-triazole 
• 123888-46-0 5-Amino-4-(N-cyanomethyl)iminomethyl-1-phenyl-1,2,3-triazole 
• 123888-47-1 5-Amino-4-(N-isopropyl)iminomethyl-1-phenyl-1,2,3-triazole 
• 123888-52-8 1-Isopropyl-4-(N-phenyl)amidino-1,2,3-triazole 
• 123888-53-9 1-t-Butyl-4-(N-phenyl)amidino-1,2,3-triazole 
• 123888-55-1 1-Phenyl-4-(N-phenyl)amidino-1,2,3-triazole 
• 123888-49-3 5-Amino-1-phenyl-4-(N-phenyl)iminomethyl-1,2,3-triazole 
• 117534-73-3 5-Oxo-3-phenyl-4,5-dihydro-3H-[1,2,3]triazolo[4,5-b]pyridine-6-carbonitrile 
• 132841-46-4 3-Phenyl-5-(phenyl-hydrazonomethyl)-3H-[1,2,3]triazol-4-ylamine 
• 123888-54-0 1-Benzyl-4-(N-phenyl)amidino-1,2,3-triazole 
• 123888-51-7 1-(Cyanomethyl)-4-(N-phenyl)amidino-1,2,3-triazole 

Relevant academic research and scientific papers

Studies on Pyrazolopyrimidine Derivatives. XVI. Preparation of Reissert Compounds from Condensed Pyrimidine Systems Catalyzed by Lewis Acids

Among various Lewis acids, aluminium chloride (AlCl3) was the most effective catalyst for the formation of the Reissert compound (21a,5-benzoyl-4,5-dihydro-1-phenyl-1H-pyrazolo-pyrimidine-4-carbonitrile) of 1-phenyl-1H-pyrazolopyr

Ring Fission of Quinazolines by Means of the Reissert Reaction

Under the Reissert reaction conditions, quinazoline (1a) afforded 2'-formylbenzanilide (2a), o-aminobenzaldehyde (3a), and N-formylbenzamide (4).Similarly, 4-methyl- (1b) and 4-ethoxyquinazoline (1c) gave the corresponding benzanilides 2b and 2c, respectively, o-aminoacetophenone (3b, from 1b), and benzamide (5).It was confirmed that the same results were obtained in the absence of the cyanide ion.A substituent at the 2-position prevented the ring fission, and only the corresponding N3-benzoyl pseudo-base (14) was obtained.The generality of the ring fission was shown by the reactions of 1-phenyl-1H-pyrazolopyrimidine (6) and 3-phenyl-3H-1,2,3-triazolopyrimidine (8), giving 5-amino-1-phenyl-1H-pyrazole-4-carbaldehyde (7) and 5-amino-1-phenyl-1H-1,2,3-triazole-4-carbaldehyde (9), respectively.Keywords - 4-substituted quinazoline; 1H-pyrazolopyrimidine; 3H-1,2,3-triazolopyrimidine; 2'-acylbenzanilide; 2-aminophenyl alkyl ketone; N-formylbenzamide; ring fission.