73122-01-7

Upstream product

• 51-48-9 L-thyroxine 

Downstream Products

• 73122-02-8 N-{2-[N-(trifluoroacetyl)-3,3',5,5'-tetraiodothyronyl]aminoethyl}-2',3'-O-isopropylidene adenosine 

Relevant academic research and scientific papers

Flavin adenine dinucleotide-labeled conjugates for use in specific binding assays

Labeled conjugates of the formula: STR1 wherein Riboflavin--Phos)2 Ribose represents the riboflavin-pyrophosphate-ribose residue in flavin adenine dinucleotide (FAD), n=2 through 6, and --CO)L is a specifically bindable ligand, or a binding analog thereof, and is preferably an iodothyronine such as thyroxine, bound through an amide bond; and intermediates produced in the synthesis of such FAD-labeled conjugates. The FAD-labeled conjugates are useful as labeled conjugates in specific binding assays for determining the ligand or a specific binding partner thereto in liquid media such as serum.

Flavin adenine dinucleotide-iodothyronine conjugates

Conjugates of the formula: STR1 wherein Riboflavin-(Phos)2 -Ribose represents the riboflavin-pyrophosphate-ribose residue in flavin adenine dinucleotide (FAD), n equals 2 through 6, Y is hydrogen or trifluoroacetyl, and β1 and β2 are, independently, hydrogen or iodine; and intermediates in the synthesis of such FAD conjugates. The FAD-iodothyronine conjugates, particularly where the iodothyronine is thyroxine, are useful as labeled conjugates in specific binding assays for determining the iodothyronine in liquid media such as serum.