73151-29-8 Usage
Description
Different sources of media describe the Description of 73151-29-8 differently. You can refer to the following data:
1. Fenticonazole nitrate is an antifungal imidazole derivative reported to be more effective
than other imidazole antifungals such as miconazole, clotrimazole and econazole. In
addition to its potent, broad-spectrum fungicidal activity, fenticonazole is also active
against some Gram-positive bacteria.
2. Fenticonazole is an imidazole with antimicrobial activity. It is active against clinical isolates of Candida species, including C. albicans, C. parapsilosis, C. tropicalis, C. krusei, and C. guilliermondii with MIC values ranging from 0.12 to 32 μg/ml. It is also active against clinical isolates of bacteria, including B. fragilis, associated with bacterial vaginosis (MICs = ≤0.03-16 μg/ml), as well as bacteria, including S. aureus and S. epidermidis, associated with skin infections with MIC values ranging from 0.03 μg/ml or less to greater than 16 μg/ml. Fenticonazole inhibits fungal growth in a guinea pig model of experimental M. canis dermatomycosis (ED50 = 0.5%, applied topically).
Chemical Properties
Off-White Solid
Uses
Broad spectrum antimycotic; also active as antibacterial. Antifungal (topical).
Definition
ChEBI: A racemate comprising equimolar amounts of (R)- and (S)-fenticonazole nitrate. Used for the treatment of vaginal candidiasis.
Brand name
Lomexin
Therapeutic Function
Antifungal
Check Digit Verification of cas no
The CAS Registry Mumber 73151-29-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,1,5 and 1 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 73151-29:
(7*7)+(6*3)+(5*1)+(4*5)+(3*1)+(2*2)+(1*9)=108
108 % 10 = 8
So 73151-29-8 is a valid CAS Registry Number.
InChI:InChI=1/C24H20Cl2N2OS/c25-19-8-11-22(23(26)14-19)24(15-28-13-12-27-17-28)29-16-18-6-9-21(10-7-18)30-20-4-2-1-3-5-20/h1-14,17,24H,15-16H2
