73154-44-6Relevant academic research and scientific papers
Approach to Isoindolinones, Isoquinolinones, and THIQs via Lewis Acid-Catalyzed Domino Strecker-Lactamization/Alkylations
Dhanasekaran, Sivasankaran,Suneja, Arun,Bisai, Vishnumaya,Singh, Vinod K.
supporting information, p. 634 - 637 (2016/03/01)
A one-pot, three-component synthesis of widely substituted isoindolinones and isoquinolinones, featuring a Lewis acid-catalyzed efficient Strecker reaction and lactamization sequence, affording products in good to high yields is reported. The method has also been extended to the synthesis of tetrahydroisoquinolines (THIQs) in high yields. (Chemical Equation Presented).
Synthesis of 1-(Aminomethyl)-1,2,3,4-tetrahydroisoquinolines and Their Actions at Adrenoceptors in Vivo and in Vitro
Beaumont, David,Waigh, Roger D.,Sunbhanich, Methi,Nott, Michael W.
, p. 507 - 515 (2007/10/02)
An improved synthesis of 1-(aminomethyl)-1,2,3,4-tetrahydroisoquinolines has been developed by using aluminum hydride reduction of 1-cyano-1,2,3,4-tetrahydroisoquinolines.Three 1-(aminomethyl)-6,7-dihydroxytetrahydroisnolines
