73179-03-0Relevant academic research and scientific papers
Bicycloheptanes as Intermediates in the Synthesis of Steroids. Total Synthesis of Estrone
Grieco, Paul A.,Takigawa, Tetsuo,Schillinger, William J.
, p. 2247 - 2251 (1980)
A synthesis of dl-estrone has been accomplished by employing the key bicycloheptene intermediate 2 prepared from ketal ester 16 via a series of reactions featuring the remarkable stereospecific alkylation of 16 with 2-(4-methoxybenzocyclobutenyl)et
