Journal of Organic Chemistry p. 2247 - 2251 (1980)
Update date:2022-08-03
Topics:
Grieco, Paul A.
Takigawa, Tetsuo
Schillinger, William J.
A synthesis of dl-estrone has been accomplished by employing the key bicyclo<2.2.1>heptene intermediate 2 prepared from ketal ester 16 via a series of reactions featuring the remarkable stereospecific alkylation of 16 with 2-(4-methoxybenzocyclobutenyl)et
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