731827-18-2Relevant academic research and scientific papers
Synthesis of 3-Amino-2-carboxamide Tetrahydropyrrolo[2,3- b ]quinolines
Pilkington, Lisa I.,Haverkate, Natalie A.,Van Rensburg, Michelle,Reynisson, Johannes,Leung, Euphemia,Barker, David
, p. 2811 - 2814 (2016)
This article communicates the first synthesis of 3-amino-2-carboxamide pyrrolo[2,3-b]quinolines and fused-ring pyrrolopyridines in an efficient synthesis via a Thorpe-Ziegler transformation. The reported synthetic route allows for a wide range of nitrogen analogues of thienopyridines - compounds which have potent bioactivities but poor aqueous solubility.
