73194-09-9Relevant academic research and scientific papers
Biomimetic Polyene Cyclizations. Total Synthesis of dl-19-Nor-4-pregnen-20-one. Asymmetric Induction by the Initiating Center
Peters, Jacobus A. M.,Posthumus, Tonny A. P.,Vliet, Nicolaas P. van,Zeelen, Filippus J.,Johnson, William S.
, p. 2208 - 2214 (1980)
dl-19-Nor-4-pregnen-20-one (2) was prepared by cationic cyclization of racemic methoxy trienyne 1.The mechanism of this reaction is discussed on the basis of byproduct analysis, deuterium labeling experiments, and the cyclization of optically active subst
Palladium-catalyzed stereocontrolled endo cyclization of 3-hydroxypropyl-1,3-cyclohexadiene leading to versatile fused tetrahydropyrans
Koroleva, Elise B.,Baeckvall, Jan-E.,Andersson, Pher G.
, p. 5397 - 5400 (2007/10/02)
A palladium-catalyzed synthesis of stereodefined fused tetrahydropyrans from 2-substituted 1,3-cyclohexadienes is presented. The reaction takes place via an intramolecular 1,4-oxidation of the conjugated diene via a (π-allyl)palladium intermediate. The st
