99861-33-3

Usage

Molecular Weight

196.24 g/mol

Appearance

Colorless to pale yellow liquid

Aroma

Pleasant aroma

Usage

Flavoring agent and fragrance ingredient

Applications

a. Cosmetics
b. Perfumes
c. Personal care products
d. Pharmaceuticals
e. Building block in the synthesis of various organic compounds

Boiling Point

270-272°C

Density

1.1 g/cm3

Solubility

Soluble in organic solvents like ethanol, acetone, and diethyl ether

Safety Precautions

a. May cause skin irritation
b. May cause eye irritation
c. May cause respiratory irritation
d. Handle with care and use appropriate personal protective equipment (PPE)

Storage

Store in a cool, dry, and well-ventilated area, away from direct sunlight and heat sources

Stability

Stable under normal conditions, but may decompose upon exposure to heat, light, or air

Regulatory Status

Subject to regulations and guidelines for use in the food, cosmetic, and pharmaceutical industries

Environmental Impact

Low to moderate environmental risk, but proper disposal and handling are necessary to minimize potential harm to the environment

Synonyms

a. Ethyl 6-oxo-1-cyclohexene-1-propanoate
b. Ethyl 6-oxocyclohex-1-ene-1-propanoate
c. Ethyl 6-oxo-1-cyclohexenyl propionate

Upstream product

• 154911-44-1 3-(1-Methylsulfinyl-2-oxocyclohexane)yl propanoate d'ethyle 
• 930-68-7 cyclohexenone 
• 140-88-5 ethyl acrylate 
• 108-94-1 cyclohexanone 
• 154911-27-0 3-(1-Methylthio-2-oxocyclohexane)yl propanoate d'ethyle 
• 52190-35-9 2-(methylthio)cyclohexanone 

Downstream Products

• 98954-51-9 3-(6-oxo-cyclohex-1-enyl)-propionic acid 
• 622852-45-3 ethyl 3-(6-hydroxycyclohex-1-en-1-yl)propanoate 
• 73194-09-9 2-(3-Hydroxy-propyl)-cyclohex-2-enol 
• 622852-54-4 ethyl 3-[5-acetoxy-6-oxocyclohex-1-en-1-yl]propanoate 
• 1350518-94-3 C₁₁H₁₃N₃O 
• 1350518-96-5 C₁₆H₂₃N₃O 

Relevant academic research and scientific papers

Total synthesis of (±)-maistemonine, (±)-stemonamide, and (±)-isomaistemonine

A full account of the total synthesis of (±)-maistemonine, (±)-stemonamide, and (±)-isomaistemo-nine is presented. Two approaches have been developed to construct the basic pyrrolo[1,2-a]azepine core of the Stemona alkaloids, featuring a tandem semipinaco

Palladium-catalyzed stereocontrolled endo cyclization of 3-hydroxypropyl-1,3-cyclohexadiene leading to versatile fused tetrahydropyrans

A palladium-catalyzed synthesis of stereodefined fused tetrahydropyrans from 2-substituted 1,3-cyclohexadienes is presented. The reaction takes place via an intramolecular 1,4-oxidation of the conjugated diene via a (π-allyl)palladium intermediate. The st

SYNTHESES DE CYCLOHEXENONES α-SUBSTITUEES VIA LA THERMOLYSE DE CETOSULFOXYDES TERTIAIRES

The sulfenylation-dehydrosulfenylation method, combined with carbon-carbon bond forming reactions, has been applied to the synthesis of some α-functionalized cyclohexenones 3.Hence, the sodium anion of the 2-methylthiocyclohexanone in THF reacts with primary, allyl and benzyl halides as well as with Michael acceptors to lead to the tertiary ketosulfides 1a-j.Further oxidation by NaIO4 and thermolysis in boiling toluene of the resulting sulfoxides 2 have been performed.The scope and limitations of this strategy are also discussed. Key Words: α-functionalized cyclohexenones; tertiary ketosulfides and ketosulfoxides; sulfenylation and deshydrosulfenylation; thermolysis.

Simple method for α-alkylation of α,β-unsaturated enones through the Michael addition

Treatment of enones and Michael acceptors with a catalytic amount of 1,8-diazabicyclo[5.4.0]undec-7-ene in 1,3-dimethyl-2-imidazolidinone at 185 °C afforded the corresponding α-substituted enones in good yields.