732-93-4

Upstream product

• 104-85-8 para-methylbenzonitrile 
• 98-07-7 Benzotrichlorid 
• 619-55-6 para-methylbenzamide 
• 874-60-2 4-methyl-benzoyl chloride 
• 7647-01-0 hydrogenchloride 
• 71-43-2 benzene 
• 22693-32-9 4-methylbenzoyl azide 

Downstream Products

• 3005-30-9 3,5-bis(4-methylphenyl)-1H-1,2,4-triazole 
• 16112-39-3 1-phenyl-3,5-di-p-tolyl-1H-1,2,4-triazole 
• 104-85-8 para-methylbenzonitrile 
• 99-94-5 p-Toluic acid 
• 619-55-6 para-methylbenzamide 

Relevant academic research and scientific papers

Traceless selenocarboxylates for the one-pot synthesis of amides and derivatives

We have recently reported a one-pot procedure for glycosyl amides synthesis using selenocarboxylate as traceless reagent. Herein, we present a further application of selenocarboxylate-azide reaction for amide bond formation on a broader range of substrates, including heterocyclic systems and fatty acid. This method proved to be highly efficient for the synthesis of primary and secondary amides, sulfonamides, imides, phosphoramide and also carbamate.

Symmetric imide compound and synthetic method thereof

The invention discloses a symmetric imide compound and a synthetic method thereof. The method comprises the steps of mixing a compound as shown in the general formula (I) and alkali in aprotic solvent, heating for reaction, and then collecting a compound as shown in the general formula (II) from the reaction product. A series of diaryl imide compounds with representative structure can be obtainedby one-step reaction of simple and easily available activated amide, which is taken as raw material.

Incorporation of molecular nitrogen into organic compounds III. Reaction of titanium-nitrogen complexes with acid halides and acid anhydrides

The titanium-nitrogen complex 1, prepared from TiCl3 or TiCl4 and Mg in THF under nitrogen reacts with acid chloride to give amide and/or imide.The cyclic imides were obtained by the reaction of titanium-isocyanate complex 3, , made from titanium-nitrogen complex 1 and carbon dioxide, and the corresponding cyclic acid anhydrides.Benzoxazone derivatives afforded the corresponding quinazoline derivatives in a similar procedure.These results indicate that molecular nitrogen was incorporated into organic compounds via titanium nitrogen complexes.

INCORPORATION OF MOLECULAR NITROGEN INTO AMIDES AND IMIDES BY USE OF TITANIUM-NITROGEN COMPLEXES

Molecular nitrogen was incorporated into amides and imides by the reaction of titanium-nitrogen complex 1 prepared from TiCl3 and Mg under N2 in THF with acyl chlorides 3.The cyclic imides 10, 12, 14 and quinazoline 16 were obtained by the reaction of isocyanate complex 6 generated by fixation of CO2 into titanium complex 1 with the corresponding cyclic anhydrides 9, 11, 13 and benzoxazone 15.