73220-38-9

Basic information

• Product Name: 3-BROMO-6-CHLOROCHROMONE
• Synonyms: 3-BROMO-6-CHLOROCHROMONE;3-BROMO-6-CHLORO-4H-CHROMEN-4-ONE
• CAS NO: 73220-38-9
• Molecular Formula: C₉H₄BrClO₂
• Molecular Weight: 259.48
• Product Categories: Chromones
• Mol File: 73220-38-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 128-130℃
• Boiling Point: 318 °C at 760 mmHg
• Flash Point: 146.1 °C
• Appearance: /
• Density: 1.835 g/cm³
• Storage Temp.: 2-8°C
• Solubility: soluble in Toluene
• CAS DataBase Reference: 3-BROMO-6-CHLOROCHROMONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-6-CHLOROCHROMONE(73220-38-9)
• EPA Substance Registry System: 3-BROMO-6-CHLOROCHROMONE(73220-38-9)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• Hazardous Substances Data: 73220-38-9(Hazardous Substances Data)

Usage

General Description

3-Bromo-6-chlorochromone is a chemical compound that belongs to the chromone family, which is known for its diverse biological activities. It is a heterocyclic compound containing a chromone ring with bromine and chlorine substituents at the 3 and 6 positions, respectively. 3-BROMO-6-CHLOROCHROMONE has shown potential as an anti-inflammatory, anti-cancer, and anti-microbial agent in various research studies. Its unique molecular structure and reactivity make it a valuable chemical for medicinal and pharmaceutical applications, and it has garnered interest for its potential therapeutic uses. Furthermore, 3-bromo-6-chlorochromone is also used as a building block for the synthesis of other pharmaceutical compounds and in the development of new drug candidates.

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Relevant articles and documents

Synthesis of 3-halochromones with simple KX halogen sources enabled by: In situ halide oxidation

On the basis of a designated in situ oxidation tactic, the synthesis of 3-halochromones has been realized for the first time by using simple KX (X = Br, I) salts as halogen sources. Instead of the free radical process, the control experiments indicate that the reported reactions proceed through a halogenium intermediate. Compared to the known synthetic methods relying on molecular halogen, haloid acid or N-halosuccinimide as the halogen source, the present method is attractive due to its higher atom economy and being more friendly to the operator, thus providing a practical complimentary approach to the preparation of useful halochromone compounds.