732275-87-5Relevant academic research and scientific papers
G-PROTEIN COUPLED RECEPTOR AGONISTS
-
Page/Page column 38-39, (2008/06/13)
Compounds of formula (I): or pharmaceutically acceptable salts thereof, are GPCR agonists and are useful as for the treatment of obesity and diabetes.
Direct synthesis of 4-arylpiperidines via palladium/copper(I)-cocatalyzed negishi coupling of a 4-piperidylzinc iodide with aromatic halides and triflates
Corley, Edward G.,Conrad, Karen,Murry, Jerry A.,Savarin, Cecile,Holko, Justin,Boice, Genevieve
, p. 5120 - 5123 (2007/10/03)
A general procedure for the synthesis of 4-arylpiperidines via the coupling of 4-(N-BOC-piperidyl)zinc iodide with aryl halides and triflates is presented. The reaction requires cocatalysis with both Cl2Pd(dppf) and a copper(I) species. An impr
