73249-94-2Relevant academic research and scientific papers
EXTENSION DE LA REACTION DE MICHAEL EN PRESENCE CsF/Si(OR)4
Boyer, J.,Corriu, R. J. P.,Perz, R.,Reye, C.
, p. 117 - 122 (2007/10/02)
An extension of the Michael reaction is described.CsF in the presence of Si(OR)4 is found to be very efficient for carrying out Michael additions of monoketones and arylacetonitriles on different kinds of Michael acceptors: α,β unsaturated ketones, esters
CATALYSE HETEROGENE PAR DES SELS ET SANS SOLVANT. III. SYNTHESE DE COMPOSES CARBONYLES α,β INSATURES A PARTIR D'ETHERS D'ENOLS SILYLES
Boyer, J.,Corriu, R. J. P.,Perz, R.,Reye, C.
, p. 157 - 166 (2007/10/02)
The reactions of silyl enol ethers with carbonyl compounds are activated by heterogeneous catalysis.Caesium fluoride is the best catalyst.Unsaturated ketones are directly obtained by condensation reactions of silyl enol ethers with aldehydes and ketones. 1,4 Addition with α,β-unsaturated carbonyl compounds gives 1,5 dicarbonyl products.This method is very convenient and the compounds obtained can easily be separated.We assume that the role of the salt in these reactions is to activate the silicon atom by anionic coordination to form a pentacoordinated silicon intermediate.
