7326-77-4

Basic information

• Product Name: 3-BENZYLSULFAMOYL-BENZOIC ACID
• Synonyms: 3-(N-BenzylsulfaMoyl)benzoic acid;Benzoic acid,3-[[(phenylMethyl)aMino]sulfonyl]-
• CAS NO: 7326-77-4
• Molecular Formula: C₁₄H₁₃NO₄S
• Molecular Weight: 291.3223
• Mol File: 7326-77-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 527.5 °C at 760 mmHg
• Flash Point: 272.8 °C
• Appearance: /
• Density: 1.366 g/cm³
• Vapor Pressure: 5.92E-12mmHg at 25°C
• Refractive Index: 1.619
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-BENZYLSULFAMOYL-BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BENZYLSULFAMOYL-BENZOIC ACID(7326-77-4)
• EPA Substance Registry System: 3-BENZYLSULFAMOYL-BENZOIC ACID(7326-77-4)

Safety Data

• Hazardous Substances Data: 7326-77-4(Hazardous Substances Data)

Usage

General Description

3-Benzylsulfamoyl-Benzoic Acid is a chemical compound that is synthesized in laboratories for various scientific purposes. 3-BENZYLSULFAMOYL-BENZOIC ACID is classified as a sulfonamide and benzoic acid which feature prominently in the field of pharmaceuticals and organic chemistry. Having these properties means it can potentially be used in the creation of various drugs or medication, most likely serving as a derivative or an intermediate in the synthesis process. Its benzoic acid aspect suggests it might be involved in reactions requiring a carboxylic acid, which frequently act as catalysts in the creation of larger, more complex compounds. However, specific detailed information on its uses and activities is not readily available, suggesting that it might still be under research and development or its use could be specific to complex laboratory syntheses.

InChI:InChI=1/C14H13NO4S/c16-14(17)12-7-4-8-13(9-12)20(18,19)15-10-11-5-2-1-3-6-11/h1-9,15H,10H2,(H,16,17)

Upstream product

• 4025-64-3 3-Carboxybenzenesulfonyl chloride 
• 100-46-9 benzylamine 
• 65-85-0 benzoic acid 

Downstream Products

• 405058-57-3 N-Benzyl-3-hydroxymethyl-benzenesulfonamide 
• 213488-05-2 Thioacetic acid S-[2-(benzhydryl-amino)-2-(3-benzylsulfamoyl-phenyl)-ethyl] ester 
• 213488-03-0 (Benzhydryl-amino)-(3-benzylsulfamoyl-phenyl)-acetic acid methyl ester 
• 213488-02-9 3-[(Benzhydryl-amino)-cyano-methyl]-N-benzyl-benzenesulfonamide 
• 213488-04-1 3-[1-(Benzhydryl-amino)-2-hydroxy-ethyl]-N-benzyl-benzenesulfonamide 
• 213488-01-8 N-benzyl-3-formylbenzenesulfonamide 

Relevant articles and documents

Design and synthesis of newer N-benzimidazol-2yl benzamide analogues as allosteric activators of human glucokinase

Allosteric activators of human glucokinase (GK) had revealed significant hypoglycemic effects for therapy of type-2 diabetes (T2D) in animal as well as human models. Some newer N-benzimidazol-2yl substituted benzamide analogues were prepared and assessed for activation of GK accompanied by molecular docking investigations for predicting the bonding interactions of these derivatives with the residues in allosteric site of GK protein. Amongst the derivatives synthesized, compounds 2 and 7 strongly increased catalytic action of GK (GK activation fold >2.0 in comparison to control) in vitro. The results of in-vitro testing were supported by the molecular docking investigations of these analogues with GK protein’s allosteric site residues (showed appreciable H-bond interactions with Arg63 residue of GK). Derivatives investigated in present study afforded few lead compounds for the discovery of harmless and strong allosteric GK activating compounds for treating T2D.

CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS

Tertiary amines containing a multiplicity of heteroaromatic substituents are useful as chemokine receptor modulators.