7327-69-7

Usage

Uses

Used in Pharmaceutical Industry:
Tetrahydro-3,5-bis(hydroxymethyl)-4H-1,3,5-oxadiazin-4-one serves as a crucial drug intermediate, facilitating the development of novel pharmaceuticals. Its role in this industry is pivotal for the synthesis of biologically active compounds, which can be utilized in the treatment of various medical conditions.
Used in Organic Chemistry:
In the realm of organic chemistry, tetrahydro-3,5-bis(hydroxymethyl)-4H-1,3,5-oxadiazin-4-one is employed as a key component in the synthesis of complex organic molecules. Its unique structure and reactivity contribute to the advancement of organic synthesis techniques and the creation of new chemical entities.
Used in Material Science:
tetrahydro-3,5-bis(hydroxymethyl)-4H-1,3,5-oxadiazin-4-one also finds applications in material science, where it may be incorporated into the design and development of new materials with specific properties. Its potential use in this field could lead to innovations in material properties and applications, such as in the creation of novel polymers or other advanced materials.

InChI:InChI=1/C5H10N2O4/c8-1-6-3-11-4-7(2-9)5(6)10/h8-9H,1-4H2

Upstream product

• 7388-44-5 3,5-bis(methoxymethyl)perhydro-1,3,5-oxadiazin-4-one 

Relevant academic research and scientific papers

Quantitative and qualitative 1H, 13C, and 15N NMR spectroscopic investigation of the urea-formaldehyde resin synthesis

Urea-formaldehyde resins are bulk products of the chemical industry. Their synthesis involves a complex reaction network. The present work contributes to its elucidation by presenting results from detailed NMR spectroscopic studies with different methods. Besides1H NMR and13C NMR, 15N NMR spectroscopy is also applied.15N-enriched urea was used for the investigations. A detailed NMR signal assignment and a model of the reaction network of the hydroxymethylation step of the synthesis are presented. Because of its higher spectral dispersion and the fact that all key reactions directly involve the nitrogen centers,15N NMR provides a much larger amount of detail than do1H and13C NMR spectroscopy. Symmetric and asymmetric dimethylol urea can be clearly distinguished and separated from monomethylol urea, trimethylol urea, and methylene-bridged urea. The existence of hemiformals of methylol urea is confirmed. 1,3,5-Oxadiazinan-4-on (uron) and its derivatives were not found in the reaction mixtures investigated here but were prepared via alternative routes. The molar ratios of formaldehyde to urea were 1, 2, and 4, the pH values 7.5 and 8.5, and the reaction temperature 60 °C. Copyright 2014 John Wiley & Sons, Ltd. 15N-enriched urea is used in combination with quantitative15N and13C NMR spectroscopy and a Virtual Reference. This allows for a detailed peak assignment and absolute quantification of the early steps of this industrial process, which involves a complex reaction network. A detailed peak assignment for all three nuclei, a full quantitative description of the reaction mixture's composition and a model describing changes in shift depending on formaldehyde substitution are given. Copyright