73278-47-4Relevant academic research and scientific papers
Alkyl- and alkoxy-substituted lamtidine analogues: Synthesis and H2-antagonistic activity. 38th Communication: H2-antihistaminics
Bonjean,Schunack
, p. 501 - 507 (2007/10/02)
In studies on the structure-activity relationships of histamine H2-receptor antagonists, lamtidine analogous derivatives of ortho-, meta- and para-substituted piperidinomethylphenoxypropylamines bearing an additional substituent on the aromatic
1,2,4-TRIAZOLE-3,5-DIAMINE DERIVATIVES
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, (2008/06/13)
The invention relates to compounds of the formula (I) STR1 and physiologically acceptable salts, hydrates and bioprecursors thereof, in whichR 1 and R 2 represent hydrogen, an aliphatic or cycloaliphatic group, or R 1 and R 2 together with the nitrogen atom form a 5 to 10 membered heterocyclic ring:Alk represents a straight or branched alkylene chain;Q represents furan, thiophen or benzene ring which is incorporated into the rest of the molecule; X represents--CH 2--, STR2--O--or--S--where R 6 represents hydrogen or methyl;n represents zero, 1 or 2; m represents 2, 3 or 4;R 3 represents hydrogen, a substituted or unsubstituted aliphatic or aryl group and;R 4 and R 5, which may be the same or different, each represent hydrogen, a substituted or unsubstituted aliphatic, aryl, or together with the nitrogen atom form a heterocyclic group.
