73279-03-5

Upstream product

• 110-89-4 piperidine 
• 123-08-0 4-hydroxy-benzaldehyde 
• 73152-41-7 4-(piperidin-1-ylmethyl)phenol 
• 94662-38-1 2-[3-(4-Piperidin-1-ylmethyl-phenoxy)-propyl]-isoindole-1,3-dione 

Downstream Products

• 115063-09-7 C₂₃H₂₈N₄O₂ 
• 94662-39-2 N-[3-[4-(1-piperidinylmethyl)phenoxy]propyl]thieno[3,4-d]isothiazol-3-amine 1,1-dioxide 
• 73278-47-4 1-methyl-N₅-[3-[4-(1-piperidinylmethyl)phenoxy]-propyl]-1H-1,2,4-triazole-3,5-diamine 

Relevant academic research and scientific papers

Alkyl- and alkoxy-substituted lamtidine analogues: Synthesis and H2-antagonistic activity. 38th Communication: H2-antihistaminics

In studies on the structure-activity relationships of histamine H2-receptor antagonists, lamtidine analogous derivatives of ortho-, meta- and para-substituted piperidinomethylphenoxypropylamines bearing an additional substituent on the aromatic

BENZO-FUSED HETEROCYCLIC ANTI-ULCER AGENTS

Compounds of the formula: STR1 wherein B is a moiety having the formula: STR2 R is mono-or dihalo, amino, nitro, cyano, hydroxy, trifluoromethyl, mercapto, lower alkyl, lower alkoxy, alkanoyl, cycloalkyl of 4-7 carbon atoms, carboxy, alkoxycarbonyl, mono-or di-lower alkyl substituted amino, alkanoylamino, lower alkyl thio, lower alkylsulfonyl, sulfamoyl, lower alkyl substituted sulfamoyl, phenyl or phenyl substituted with halo, lower alkyl, lower alkoxy, trifluoromethyl, hydroxy, amino, cyano or nitro.X is SO 2, SO, S or C=O; andA is amine selected from the group STR3 , wherein R 1 is hydrogen or R 2 CH 2 wherein R 2 is mono-or diloweralkylamino, mono-or di-N-lower alkylaminoloweralkyl, (2-furyl) methylamino, benzylamino, lowercycloalkylamino, 1-pyrrolidinyl, 1-piperidinyl, 1-hexahydroazepinyl, 1-octahydroazocinyl, 3-thiazolidinyl, 4-morpholinyl or 4-thiomorpholinyl; R 3 is hydrogen or (1-piperidinyl) methyl with the proviso that when R 3 is (1-piperidinyl)methyl, R 1 is hydrogen; n is 1 to 4, and the pharmacologically acceptable salts thereof.

1,2,4-TRIAZOLE-3,5-DIAMINE DERIVATIVES

The invention relates to compounds of the formula (I) STR1 and physiologically acceptable salts, hydrates and bioprecursors thereof, in whichR 1 and R 2 represent hydrogen, an aliphatic or cycloaliphatic group, or R 1 and R 2 together with the nitrogen atom form a 5 to 10 membered heterocyclic ring:Alk represents a straight or branched alkylene chain;Q represents furan, thiophen or benzene ring which is incorporated into the rest of the molecule; X represents--CH 2--, STR2--O--or--S--where R 6 represents hydrogen or methyl;n represents zero, 1 or 2; m represents 2, 3 or 4;R 3 represents hydrogen, a substituted or unsubstituted aliphatic or aryl group and;R 4 and R 5, which may be the same or different, each represent hydrogen, a substituted or unsubstituted aliphatic, aryl, or together with the nitrogen atom form a heterocyclic group.