7331-99-9Relevant academic research and scientific papers
Synthesis of alcohols from m-fluorophenylsulfones and dialkylboranes: Application to the C14-C35 building block of E7389
Liu, Lei,Henderson, James A.,Yamamoto, Akihiko,Bremond, Paul,Kishi, Yoshito
supporting information; experimental part, p. 2262 - 2265 (2012/06/30)
The reaction of m-fluorophenylsulfone anions with dialkylboranes, followed by alkaline hydroperoxide oxidation, yields alcohols in high yields. Optimization of the process, scope and limitation, and application to the synthesis of one of the C14-C35 building blocks of E7389, a right half analogue of halichondrin B, are reported.
Synthesis of (+)-trixagol and its enantiomer, the terpenoid side chain of (-)-agelasine E
Bakkestuen, Anne Kristin,Gundersen, Lise-Lotte
, p. 115 - 121 (2007/10/03)
The naturally occurring γ-cyclogeranylgeraniol called (+)-trixagol has been synthesised for the first time. Trixagol was readily available in five steps from (S)-2,2-dimethyl-6-methylene-1-cyclohexanemethanol. The enantiomer of trixagol, which equates to
