73316-17-3

Upstream product

• 63472-21-9 3-([1,1'-biphenyl]-4-yloxy)propanoic acid 
• 92-69-3 4-Phenylphenol 
• 63472-20-8 3-(biphenyl-4-yloxy)-propionitrile 
• 92-66-0 4-bromo-1,1'-biphenyl 

Downstream Products

• 130688-97-0 3-[1-Benzo[1,3]dioxol-5-yl-meth-(E)-ylidene]-6-phenyl-chroman-4-one 
• 73316-13-9 C₁₇H₁₄N₂O₃ 
• 130688-95-8 3-[1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-6-phenyl-chroman-4-one 
• 130688-96-9 3-[1-(3,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-6-phenyl-chroman-4-one 
• 130688-94-7 3-[1-(2-Methoxy-phenyl)-meth-(E)-ylidene]-6-phenyl-chroman-4-one 
• 1416006-07-9 4-(4-methoxyphenyl)-6-phenyl-2H-chromene 

Relevant academic research and scientific papers

Rapid synthesis of 4-arylchromenes from ortho-substituted alkynols: A versatile access to restricted iso combretastatin A-4 analogues as antitumor agents

Potent anticancer 4-arylchromene agents 6, as restricted isoCA-4 analogues, were prepared with excellent yields by a rapid and versatile synthetic pathway. First, in the presence of PTSA in EtOH, a variety of arylalkynols 9 were transformed into substitut

Copper(ii)-catalyzed C-O coupling of aryl bromides with aliphatic diols: Synthesis of ethers, phenols, and benzo-fused cyclic ethers

A highly efficient copper-catalyzed C-O cross-coupling reaction between aryl bromides and aliphatic diols has been developed employing a cheaper, more efficient, and easily removable copper(ii) catalyst. A broad range of aryl bromides were coupled with aliphatic diols of different lengths using 5 mol% CuCl2 and 3 equivalents of K2CO3 in the absence of any other ligands or solvents to afford the corresponding hydroxyalkyl aryl ethers in good to excellent yields. In this newly developed protocol, aliphatic diols have multilateral functions as coupling reactants, ligands, and solvents. The resulting hydroxyalkyl aryl ethers were further readily converted into the corresponding phenols, presenting a valuable alternative way to phenols from aryl bromides. Furthermore, it was demonstrated that they are useful intermediates for more advanced molecules such as benzofurans and benzo-fused cyclic ethers. This journal is

Phenyl or phenoxy substituted spiro-imidazolidinedione derivatives

Novel phenyl or phenoxy substituted spiro-imidazolidinedione derivatives useful as aldose reductase inhibitors and as therapeutic agents for the treatment of chronic diabetic complications are disclosed. The derivatives include the phenyl or phenoxy subst