73333-83-2Relevant academic research and scientific papers
Basic Methanolysis of N-Aryl-N-phenylbenzamides
Broxton, Trevor J.,Deady, Leslie W.,Rowe, Jeffrey E.
, p. 2404 - 2408 (1980)
The mechanism of basic methanolysis of a series of N-aryl-N-phenylbenzamides in methanol and in 80percent Me2SO-methanol has been studied.Comparison of Hammett ρ values with results in the literature suggest that in methanol the rate-determining step is s
A simple copper-catalyzed synthesis of tertiary acyclic amides
Racine, Emilie,Monnier, Florian,Vors, Jean-Pierre,Taillefer, Marc
supporting information; experimental part, p. 2818 - 2821 (2011/07/09)
The N-arylation of aromatic and aliphatic secondary acyclic amides, known to be poor nucleophiles, has been accomplished using a simple and cheap copper catalytic system. The corresponding tertiary acyclic amides, which can be found in numerous biologically active compounds, have been obtained in good to excellent yields.
