73340-33-7

Usage

Uses

Used in Dye Production:
Phenol, 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis[2-nitrois employed as a key intermediate in the production of various dyes. Its unique chemical structure allows for the creation of a wide range of colors and properties, making it valuable in this application.
Used in Pharmaceutical Industry:
This phenol derivative is utilized in the synthesis of pharmaceuticals, contributing to the development of new drugs and medications. Its reactivity plays a crucial role in forming the desired molecular structures for effective pharmaceutical compounds.
Used as a Laboratory Reagent:
Phenol, 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis[2-nitroserves as a versatile reagent in laboratory settings, where it can be used for various chemical reactions and analyses. Its properties make it suitable for research and development purposes in the scientific community.
Used in Chemical Research:
Due to its high reactivity, this phenol derivative is also used in chemical research to explore new reaction pathways and develop innovative chemical processes. It can be a valuable tool for scientists working on advanced chemical synthesis and material development.

Upstream product

• 462-06-6 fluorobenzene 
• 1478-61-1 4,4'-(hexafluoroisopropylidene)diphenol 

Downstream Products

• 83558-87-6 2,2-bis(3-amino-4-hydroxyphenyl)hexafluoropropane 
• 61005-79-6 2,2-bis(3,4-di-o-aminophenyl)hexafluoropropane 
• 3016-76-0 1,1,1,3,3,3-hexafluoro-2,2-di(3,4-dicarboxyphenyl)-propane 
• 1107-00-2 4,4'-(1,1,1,3,3,3-hexafluoroisopropylidene)diphthalic anhydride 
• 116891-73-7 2,2-bis-(3-nitro-4-tosyloxyphenyl)-hexafluoropropane 
• 116891-71-5 2,2-bis-(4-mesyloxy-3-nitrophenyl)-hexafluoropropane 

Relevant academic research and scientific papers

Method for preparing 2, 2-bis (3-nitro-4-hydroxyphenyl) hexafluoropropane by microchannel reactor

The invention discloses a method for preparing 2, 2-bis (3-nitro-4-hydroxyphenyl) hexafluoropropane by a microchannel reactor. The method comprises the following steps: (1) fully mixing and preheating bisphenol AF and an organic solvent to obtain a bisphenol AF solution, and respectively introducing the bisphenol AF solution and a preheated nitrating agent as two strands of materials into a continuous flow microchannel reactor through a metering pump; (2) controlling the flow rate of the material through a metering pump, enabling the bisphenol AF solution and the nitrating agent to respectively enter a micro-channel reactor module for mixed reaction, and enabling a product to flow out from an outlet of the reactor; and (3) carrying out post-treatment on the material obtained from the outlet of the microchannel reactor to obtain a pure product of 2, 2-bis (3-nitro-4-hydroxyphenyl) hexafluoropropane. The method provided by the invention can realize continuous production, has mild reaction conditions, high reaction efficiency and high yield, and is suitable for industrial production.

Preparation method of 5, 5'-(perfluoropropane-2, 2-diyl) bis (2-(allyloxy) aniline)

The invention provides a preparation method of 5, 5'-(perfluoropropane-2, 2-diyl) bis (2-(allyloxy) aniline), and relates to the technical field of synthesis of chemical intermediates. The preparation method comprises the steps of dissolving 4, 4 '-(hexafluoroisopropylidene) diphenol in glacial acetic acid and nitric acid, reacting to obtain 2, 2-bis (3-nitro-4-hydroxyphenyl) hexafluoropropane, dissolving the product in acetonitrile, adding potassium carbonate and 3-bromopropylene, and reacting to obtain 5, 5'-(perfluoropropane-2, 2-diyl) bis (2-(allyloxy) nitrobenzene); and reacting 5, 5 '-(perfluoropropane-2, 2-diyl) bis (2-(allyloxy) nitrobenzene), iron powder and ammonium chloride to obtain 5, 5'-(perfluoropropane-2, 2-diyl) bis (2-(allyloxy) aniline). The synthetic route is mild in reaction condition, simple in reaction and post-treatment process operation, low in reaction danger coefficient, low in production cost and suitable for industrial large-scale production.

Preparation method for bis(3-amino-4-hydroxyphenyl)hexafluoropropane

The invention belongs to the technical field of electronic chemical materials, and more specifically relates to a preparation method for bis(3-amino-4-hydroxyphenyl)hexafluoropropane. The preparationmethod for the bis(3-amino-4-hydroxyphenyl)hexafluoropropane disclosed by the invention comprises the following steps: step 1, introducing hexafluoroacetone into a reactant (I) in the presence of a catalyst for a reaction so as to obtain a compound (II); step 2, allowing the compound (II) obtained in the step 1 with nitric acid and sulfuric acid so as to obtain a compound (III); step 3, adding thecompound (III) obtained in the step 2 into inorganic base for a reaction so as to obtain a compound (IV); and step 4, carrying out catalytic hydrogenation on the compound (IV) obtained in the step 3so as to obtain the bis(3-amino-4-hydroxyphenyl)hexafluoropropane.

Environmentally friendly preparation technology of 2,2-bis(3-nitro-4-hydroxyphenyl)hexafluoropropane

The invention relates to an environmentally friendly preparation technology of 2,2-bis(3-nitro-4-hydroxyphenyl)hexafluoropropane. The technology comprises the following steps: preparing a 1,2-dichloroethane solution of bisphenol AF; preparing a 1,2-dichloroethane solution of N2O5; carrying out a nitration reaction to generate 2,2-bis(3-nitro-4-hydroxyphenyl)hexafluoropropane; filtering the 2,2-bis(3-nitro-4-hydroxyphenyl)hexafluoropropane, washing the 2,2-bis(3-nitro-4-hydroxyphenyl)hexafluoropropane, and layering the 2,2-bis(3-nitro-4-hydroxyphenyl)hexafluoropropane to obtain a lower layer organic phase; carrying out dehydration drying, filtering the obtained material, and carrying out vacuum distillation to obtain crude 2,2-bis(3-nitro-4-hydroxyphenyl)hexafluoropropane; and re-crystallizing the crude 2,2-bis(3-nitro-4-hydroxyphenyl)hexafluoropropane, cooling the re-crystallized 2,2-bis(3-nitro-4-hydroxyphenyl)hexafluoropropane, filtering the cooled 2,2-bis(3-nitro-4-hydroxyphenyl)hexafluoropropane, and carrying out vacuum drying to obtain purified 2,2-bis(3-nitro-4-hydroxyphenyl)hexafluoropropane. The preparation technology adopts dinitrogen pentoxide (N2O5) as a nitration agent and allows the reaction to be carried out a low temperature, so pollution of waste acids is thoroughly eliminated, and toxic, harmful and highly risky byproducts are reduced, and the nitration reaction is clean and environmentally friendly.

Method of producing 2,2-bis(3-nitro-4-hydroxyphenyl)hexafluoropropane

Disclosed herein is a method of producing 2,2-bis(3-nitro-4-hydroxphenyl)hexafluoropropane, which comprises (a) preparing 2,2-bis(4-hydroxyphenyl)hexafluoropropane and a lower fatty acid; and (b) allowing the 2,2-bis(4-hydroxyphenyl)hexafluoropropane to react with nitric acid in the lower fatty acid.