7335-32-2

Usage

InChI:InChI=1/C10H13NO2/c1-3-13-10(12)9-6-8(11)5-4-7(9)2/h4-6H,3,11H2,1-2H3

Upstream product

• 124358-24-3 ethyl 2-methyl-5-nitrobenzoate 
• 1975-52-6 5-nitro-o-toluic acid 

Downstream Products

• 34265-55-9 ethyl 3-hydroxy-6-methylbenzoate 
• 896160-38-6 5-(3-(2-cyanopropan-2-yl)benzamido)-2-methylbenzoic acid 
• 1351237-97-2 5-(3-(2-cyanopropan-2-yl)benzamido)-2-methyl-N-(thieno[2,3-b]pyrazin-6-yl)benzamide 
• 1351238-76-0 ethyl 5-(3-(2-cyanopropan-2-yl)benzamido)-2-methylbenzoate 
• 1315380-88-1 C₁₉H₁₇ClF₃NO₃ 
• 1315380-92-7 (E)-tert-butyl 5-(2-methyl-5-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamido)styryl)pyrazin-2-ylcarbamate 
• 1315380-91-6 N-(3-formyl-4-methylphenyl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamide 
• 1315380-90-5 N-(3-(hydroxymethyl)-4-methylphenyl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamide 
• 1315380-89-2 ethyl 2-methyl-5-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamido)benzoate 
• 359629-91-7 ethyl 5-bromo-2-methylbenzoate 
• 210987-78-3 (1R,3aS,4S,7aR)-1-((R)-1,5-Dimethyl-hexyl)-4-{2-[5-(2-methoxy-ethoxymethoxy)-2-methyl-phenyl]-ethyl}-7a-methyl-octahydro-inden-5-one 
• 169217-42-9 Calicoferol E 
• 210987-59-0 5-(2-Methoxy-ethoxymethoxy)-2-methyl-benzoic acid ethyl ester 
• 210987-74-9 2-Iodomethyl-4-(2-methoxy-ethoxymethoxy)-1-methyl-benzene 

Relevant academic research and scientific papers

THIENO (2, 3B) PYRAZINE COMPOUNDS AS B-RAF INHIBITORS

The invention relates to compounds according to general Formula (I) or a pharmaceutically acceptable salt thereof. The compounds can be used for the treatment of cancer.

THIENO (2, 3B) PYRAZINE COMPOUNDS AS B - RAF INHIBITORS

The invention relates to compounds according to general Formula (I) or a pharmaceutically acceptable salt thereof. The compounds can be used for the treatment of cancer.

Synthesis of symmetric diester-functionalised Troeger's base analogues

The yields of ester-functionalised Troeger's base analogues are dramatically improved by incorporating an electron-donating group on the aromatic ring and/or enhancing solubil- ity of the aniline unit. In addition to 2,8-diester compounds, 1,7-, 3,9- and 4,10-diester-functionalised Troeger's base analogues have been prepared for the first time.

ISOINDOLINE COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES

Disclosed is a compound of Formula (I) in which W and R1-R6 are defined herein. Also disclosed is a method of treating spinal muscular atrophy, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced directly or indirectly by mutation or frameshift.

COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES

Compounds of Formula (I) or (II) useful for the treatment of spinal muscular atrophy or other uses, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes

Selective deprotection of isopropyl esters, carbamates and carbonates with aluminum chloride

The O-isopropyl bond of isopropyl esters, carbamates, and carbonates has been effectively and selectively cleaved by treatment with AlCl3 in nitromethane at 0-50 °C to give carboxylic acids, amines, and alcohols, respectively, in good to excell

Synthesis of calicoferol E and astrogorgiadiol, two marine 9,10- secosteroids

The synthesis of two marine 9,10-secosteroids, calicoferol E and astrogorgiadiol, has been achieved starting from vitamin D3. The conceived approach establishes a general convergent Strategy toward the synthesis of 9,10-secosteroids.