73352-51-9

Upstream product

• 74124-79-1 di(succinimido) carbonate 
• 17996-13-3 benzyl 4-hydroxybutylcarbamate 
• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 73352-66-6 bis-N-benzyloxycarbonyl-1-N-(4-benzyloxycarbonylaminobutyloxycarbonyl)gentamicin B 
• 73362-94-4 1-N-(4-aminobutyloxycarbonyl)gentamicin B 

Relevant academic research and scientific papers

OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION

The present invention relates to ligand conjugates of oligonucleotides (e.g., iRNA agents) and methods for their preparation. The ligands are derived primarily from monosaccharides These conjugates are useful for the in vivo delivery of oligonucleotides.

Semisynthetic Aminoglycoside Antibacterials. Part 10. Synthesis of Novel 1-N-Aminoalkoxycarbonyl and 1-N-Aminoalkylcarboxamido Derivatives of Sisomicin, Gentamicin B, Gentamicin C1a, and Kanamycin A

Suitably protected derivatives of sisomicin, 5-epi-sisomicin, gentamicin B, gentamicin C1a, and kanamycin A have been converted into a series of 1-N-alkoxycarbonyl, 1-N-aminoalkoxycarbonyl, 1-N-carboxamido, 1-N-alkylcarboxamido, and 1-N-aminoal

1-N-substituted derivatives of 4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols

Novel 1-N-aminoalkyl (oxycarbonyl or carboxamido or thiocarboxamido) derivatives of 4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols, useful as antibacterial agents, are described.