73357-23-0

Upstream product

• 7417-21-2 2-(3,4-dimethoxyphenyl)ethyl alcohol 
• 50-00-0 formaldehyd 
• 7509-11-7 1,2-dimethoxy-4-methyl-5-nitrobenzene 
• 2982-53-8 methyl 2-(4,5-dimethoxy-2-nitrophenyl)acetate 
• 65907-71-3 1,2-dimethoxy-4-nitro-5-vinylbenzene 
• 20357-25-9 6-nitroveratraldehyde 
• 93-40-3 (3,4-Dimethoxyphenyl)acetic acid 
• 73357-18-3 (4,5-dimethoxy-2-nitrophenyl)acetic acid 

Downstream Products

• 90869-96-8 2-nitro-4,5-dimethoxyphenethyl chloride 
• 179691-30-6 2-(4,5-dimethoxy-2-nitrophenyl)ethyl chloroformate 
• 110905-12-9 4,5-dimethoxy-2-(2-chloroethyl)-anline 
• 110905-13-0 2-(2-chloroethyl)-4,5-dimethoxyphenyl isocyanate 
• 110934-60-6 N-(tert-butoxycarbonyl)-2-(2-chloroethyl)-4,5-dimethoxyaniline 
• 110934-61-7 N-benzoyl-2-(2-chloroethyl)-4,5-dimethoxyaniline 
• 110905-10-7 1-Benzoyl-6-methoxy-7a-phenyl-1,2,3,7a-tetrahydro-indol-5-one 
• 110905-14-1 [2-(2-Chloro-ethyl)-4,4,5-trimethoxy-cyclohexa-2,5-dien-(Z)-ylidene]-carbamic acid tert-butyl ester 
• 110934-59-3 N-[2-(2-Chloro-ethyl)-4,4,5-trimethoxy-cyclohexa-2,5-dien-(Z)-ylidene]-benzamide 
• 110905-18-5 7a-[2-(2-Fluoro-ethyl)-4,5-dimethoxy-phenyl]-6-methoxy-5-oxo-2,3,5,7a-tetrahydro-indole-1-carboxylic acid tert-butyl ester 
• 2982-53-8 methyl 2-(4,5-dimethoxy-2-nitrophenyl)acetate 
• 15889-93-7 (+/-)-crispine A 
• 73357-26-3 Methanesulfonic acid 2-(5-benzyloxy-4-methoxy-2-nitro-phenyl)-ethyl ester 
• 73357-25-2 2-(5-Benzyloxy-4-methoxy-2-nitro-phenyl)-ethanol 

Relevant academic research and scientific papers

Direct Arylation of Distal and Proximal C(sp3)-H Bonds of t-Amines with Aryl Diazonium Tetrafluoroborates via Photoredox Catalysis

A visible light-mediated arylation protocol for t-amines has been reported through the coupling of γ- and α-amino alkyl radicals with different aryl diazonium salts using Ru(bpy)3Cl2·6H2O as a photocatalyst. Structurally different 9-aryl-9,10-dihydroacridine, 1-aryl tetrahydroisoquinoline, hexahydropyrrolo[2,1-a]isoquinoline, and hexahydro-2H-pyrido[2,1-a]isoquinoline frameworks with different substitution patterns have been synthesized in good yield using this methodology.

A Photo-responsive Small-Molecule Approach for the Opto-epigenetic Modulation of DNA Methylation

Controlling the functional dynamics of DNA within living cells is essential in biomedical research. Epigenetic modifications such as DNA methylation play a key role in this endeavour. DNA methylation can be controlled by genetic means. Yet there are few c

Amine derivatives, processes for producing them and a use of them as antiarrhythmic drugs

PCT No. PCT/JP95/01138 Sec. 371 Date May 27, 1997 Sec. 102(e) Date May 27, 1997 PCT Filed Jun. 7, 1995 PCT Pub. No. WO96/04231 PCT Pub. Date Feb. 15, 1996Novel amine derivatives of the following general formula (I): (wherein) A may denote -(CH2)-O-, -(CH2)2-O-, or -(CH2)2-NH-; B may denote -(CH2)2-; R1 may denote a hydrogen atom, a halogen atom, a nitro group, a 1-pyrrolyl group, an acetamido group, an amino group or a dimethylamino group; R2 may denote a hydrogen atom or a nitro group; R3 and R4 may denote a hydrogen atom; R8a and R8b which are the same may denote a chlorine atom or a methoxy group; R9 may denote a hydrogen atom or an amino group; R may denote a methyl group; and X may denote a methanesulfonamido group, a 1-imidazolyl group or a nitro group or a salts thereof are useful as antiarrhythmic drugs.

Synthesis and biological activity of KCB-328 and its analogues: Novel class III antiarrhythmic agents with little reverse frequency dependence

A series of 3,4-dimethoxyphenethylamine derivatives was prepared, and their prolongation effects on effective refractory period of contractile response (ERPc) and action potential duration (APD) in isolated guinea-pig papillary muscles at 1 Hz and 3 Hz were examined. SAR studies led to the identification of KCB-328 (51) which is a novel class III antiarrhythmic agent with little reverse frequency dependence.

New photolabile protecting groups in nucleoside and nucleotide chemistry - Synthesis, cleavage mechanisms and applications

New photolabile protecting groups have been found in the 2-(2- nitrophenyl)ethoxycarbonyl and the 2-(2-nitrophenyl)ethylsulfonyl group, respectively. The influence of substituents at the phenyl ring as well as the side-chain has been investigated regarding the photolysis rates on irradiation at 365 mn. β-Branching in the side-chain leads to highly increased rates of photodeprotection. A new type of photocleavage mechanism consisting of a photoinduced β-elimination process is proposed.

Nucleoside derivatives with photolabile protective groups

The invention relates to nucleoside derivatives having photolabile protective groups of the general formula (I) STR1 in which R1 =H, NO2, CN, OCH3, halogen or alkyl or alkoxyalkyl having 1 to 4 C atoms R2 =H, OCH3 R3 =H, F, Cl, Br, NO2 R4 =H, halogen, OCH3, or an alkyl radical having 1 to 4 C atoms R5 =H or a usual functional group for preparing oligonucleotides R6 =H, OH, halogen or XR8, where X=O or S and R8 represents a protective group usual in nucleotide chemistry, B=adenine, cytosine, guanine, thymine, uracil, 2,6-diaminopurin-9-yl, hypoxanthin-9-yl, 5-methylcytosin-1-yl, 5-amino-4-imidazolcarboxamid-1-yl, or 5-amino-4-imidazolcarboxamid-3-yl, where in the case of B=adenine, cytosine or guanine, the primary amino function optionally exhibits a permanent protective group. These derivatives may be used for the light-controlled synthesis of oligonucleotides on a DNA chip.