733717-87-8Relevant academic research and scientific papers
Substituted morpholine-2S-acetic acid derivatives: SCH 50911 and related compounds as novel GABA(B) antagonists
Blythin, David J.,Kuo, Shen-Chun,Shue, Ho-Jane,McPhail, Andrew T.,Chapman, Richard W.,Kreutner, William,Rizzo, Charles,She, Hoyan S.,West, Robert
, p. 1529 - 1534 (1996)
The synthesis and GABA(B) antagonist activity of a series of substituted morpholine-2-acetic acid derivatives is described. Resolution of the lead compound from the series produces one active and one inactive enantiomer. X- ray analysis of a halogenated derivative (25) of the active enantiomer Sch 50911 (23) shows that it possesses the 2S configuration.
