733768-87-1Relevant academic research and scientific papers
Iodide as a Nucleophilic Trigger in Aryne Three-Component Coupling for the Synthesis of 2-Iodobenzyl Alcohols
Bhattacharjee, Subrata,Guin, Avishek,Gaykar, Rahul N.,Biju, Akkattu T.
supporting information, p. 4383 - 4387 (2019/06/08)
The synthetic potential of KI as the iodide source in aryne three-component coupling has been demonstrated using aldehydes as the third component. This mild and transition-metal-free coupling reaction allowed the straightforward synthesis of 2-iodobenzyl alcohols in moderate to good yields with good functional group compatibility. Moreover, KBr and KCl could be used as the nucleophilic trigger in this aryne multicomponent coupling (MCC) and N-methylisatin and CO2 could be used as the electrophilic third components.
Synthesis of benzo[b]naphtho[2,3-d]furan-6,11-dione via one-pot remote anionic fries rearrangement and metalation reaction
Azevedo, Mariangela S.,Alves, Glaucia B. C.,Cardoso, Jari N.,Lopes, Rosangela S. C.,Lopes, Claudio C.
, p. 1262 - 1268 (2007/10/03)
The use of a lithiation reaction to transform the bromo-arylcarbamate 8a into the corresponding benzo[b]naphtho[2,3-d]furan-6,11-dione (2) is described.
