7338-50-3

Basic information

• Product Name: 6-Phenylfulvene
• Synonyms: (2,4-Cyclopentadiene-1-ylidenemethyl)benzene;(2,4-Cyclopentadienylidenemethyl)benzene;1-Benzylidene-2,4-cyclopentadiene;2,4-Cyclopentadien-1-ylidenephenylmethane;5-Benzylidene-1,3-cyclopentadiene;6-Phenylfulvene
• CAS NO: 7338-50-3
• Molecular Formula: C₁₂H₁₀
• Molecular Weight: 154.21
• Mol File: 7338-50-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-Phenylfulvene(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Phenylfulvene(7338-50-3)
• EPA Substance Registry System: 6-Phenylfulvene(7338-50-3)

Safety Data

• Hazardous Substances Data: 7338-50-3(Hazardous Substances Data)

Upstream product

• 542-92-7 cyclopenta-1,3-diene 
• 100-52-7 benzaldehyde 
• 71-43-2 benzene 
• 57918-63-5 (Z)-styryl iodide 
• 1066-54-2 trimethylsilylacetylene 
• 97874-96-9 7-Benzylidenbicyclo<2.2.1>hepta-2,5-dien 
• 17306-11-5 allyl(5-cyclopentadienyl)dimethylsilane 

Downstream Products

• 102870-26-8 (4aRS,7aSR)-5-Benzyliden-5,7a-dihydro-2,3-bis(methylthio)-4aH-cyclopenta-1,4-dithiin 
• 144760-01-0 2-diphenylmethyl-6,6-diphenylfulvene 
• 67654-88-0 7-benzylidene-2,3-benzonorborna-2,5-diene 
• 270921-99-8 7-benzylidene-2,3-dioxa-bicyclo[2.2.1]hept-5-ene 
• 679835-94-0 3-(4-chloro-phenyl)-1-hydroxy-4-phenyl-2,3,4,7a-tetrahydro-1H-[2]pyrindine-1-carboxylic acid methyl ester 

Relevant articles and documents

Thermic conversion of benzene into 6-phenylfulvene with high yield mediated by GaP nanocrystals

With GaP nanocrystals being used in a close reaction system, 6-phenylfulvene is successfully obtained via a high yield thermic conversion from benzene, which provides the possibility of applying nanocrystals to mediate organic reactions.

New titanocene derivatives with high antiproliferative activity against breast cancer cells

The synthesis and characterization of some new titanocene-complexes, having a ethenyl-phenoxide or a benzyl group as substituents of the cyclopentadienyl rings, are reported. The synthesized compounds have been evaluated for their cytotoxic potential against two human breast cancer cell lines, that is: MCF7 and SkBr3. Most of these compounds have shown significant cytotoxic effects, compared to cisplatin, in MTT-based cell tests.

Kinetics and Mechanism of Pyrrolidine Buffer-Catalyzed Fulvene Formation

Rapid synthesis of fulvenes is achieved using pyrrolidinium/pyrrolidine buffers in anhydrous acetonitrile. Time-dependent UV-vis absorption and NMR spectroscopy reveal that the rate and yield of fulvene formation depend strongly on both the presence of acid in the medium and the choice of solvent, and they are negatively affected by water. Kinetic data have been collected for various substrates, and the synthetic benefits of the adjusted reaction conditions are showcased. Enhancements of reaction rates are found in comparison to literature procedures. α-Unsaturated fulvenes that were previously difficult to access can now be obtained in good yields.

METALLOCENE COMPOUND, CATALYST COMPOSITION COMPRISING THE SAME, AND METHOD FOR PREPARING OLEFIN-BASED POLYMER USING THE SAME

The present invention relates to a novel metallocene compound, a catalyst composition comprising the same, and a method for preparing an olefin-based polymer using the same. According to the present invention, the metallocene compound can show excellent activity in a copolymerization reaction of ethylene and alpha-olefin, and can provide an olefin-based polymer which has low molecular weight and high content of comonomers.COPYRIGHT KIPO 2015

Synthesis, characterization and cytotoxic activity on breast cancer cells of new half-titanocene derivatives

A series of novel titanocene-complexes has been prepared and evaluated for their growth regulatory effects in MCF7 and SkBr3 breast cancer cells. The capability of some of these compound to elicit relevant repressive effects on cancer cell growth could be taken into account towards novel pharmacological approaches in cancer therapy.

An efficient catalytic method for fulvene synthesis

The effects of the nature and amount of base, substrate structure, amount of added water and solvent on the condensation of carbonyl compounds with cyclopentadiene in the presence of secondary amines were investigated. Based on these studies, a new efficient and green synthesis of fulvenes was developed.

Cp*Li as a base: application to palladium-catalyzed cross-coupling reaction of aryl-X or alkenyl-X (X=I, Br, OTf, ONf) with terminal acetylenes

The reaction of aryl-X or alkenyl-X (X=I, Br, OTf, ONf) with terminal acetylenes in the presence of a catalytic amount of Pd(OAc)2 provided the alkynylated products in good yields by using Cp*Li (Cp*=1,2,3,4,5-pentamethylcyclopentadienyl) as a base.

A novel reaction of titanacyclopentenes and aldehydes with or without Lewis acids

Oxatitanacyclopentenes were prepared in high yields from the reaction of aldehydes with titanacyclopenetens via substitution of ethylene. No insertion product was obtained in this reaction. The combination of alkynes and aldehydes played an important role in the successive formation of oxatitanacyclopentenes. Some oxatitanacyclopentenes are very stable and can be purified using column chromatography. The cooperation between Ti and LA led to very different results from that between Zr and LA.

Alkylation of carbonyl compounds with dialkylzirconocene complexes promoted by potassium t-butoxide

Potassium t-butoxide promotes alkylation of non-enolizable ketones and aldehydes by zirconocene dialkyls. The reaction proceeds with loss of cyclopentadienide ion from the metal center.

A new synthesis of substituted fulvenes

A new fulvene synthesis results from the palladium-catalyzed [2 + 2 + 2] annulation of 1 mol of a β-substituted vinyl iodide and 2 mol of a monosubstituted acetylene. This variant of the Heck reaction tolerates a wide range of substrate substituents with