73436-06-3Relevant articles and documents
AMORPHASTILBOL, AN ANTIMICROBIAL AGENT FROM AMORPHA NANA
Mitscher, Lester A.,Gollapudi, Sitaraghav Rao,Drake, Steven,Oburn, David S.
, p. 1481 - 1484 (1985)
Key Word Index - Amorpha nana; Leguminosae; amorphastilbol; 3,5-dihydroxy-7,4'-dimethoxyflavone; antimicrobial agents; chemistry; bioactivity.Abstract - Bioassay-directed fractionation of Amorpha nana demonstrated that the anti Gram positive/antitubercular constituent is amorphastilbol.The chemical structure of amorphastilbol was confirmed by chemical transformation to known (Radula variabilis) dihydroamorphastilbol and its methyl ether.Inactive 3,5-dihydroxy-7,4'-dimethoxyflavone was detected in this plant for the first time and identified by interconversion with kaempferol.All compounds were evaluated in vitro for antimicrobial spectrum and potency.