7344-61-8

Usage

InChI:InChI=1/C12H8N2O/c15-12-10-7-14-11-4-2-1-3-9(11)8(10)5-6-13-12/h1-7H,(H,13,15)

Upstream product

• 61686-64-4 1-benzyloxy-9,10-dihydro-2,9-diazaphenanthrene 
• 61686-65-5 2,5-dibromo-3-(bromomethyl)pyridine 
• 61686-62-2 2-benzyloxy-5-dibromo-3-[(N-phenyl)aminomethyl]pyridine 
• 61686-66-6 2,5-dibromo-3-[(N-phenyl)aminomethyl]pyridine 
• 3430-21-5 5-bromo-3-methyl-pyridin-2-ylamine 
• 3430-18-0 2,5-dibromo-3-methylpyridine 
• 61686-67-7 1-benzyloxy-2,9-diazaphenanthrene 
• 101617-94-1 2?chloro?3?cyano?4?methylquinoline 
• 73013-65-7 4-methyl-3-quinolinecarbonitrile 
• 146140-95-6 2-pivaloylaminophenyl boronic acid 
• 614-76-6 N-acetyl-2-bromoaniline 

Relevant academic research and scientific papers

Confirmation of the Revised Structure of Samoquasine A and a Proposed Structural Revision of Cherimoline

The identity of the natural product samoquasine A has remained obscure since its isolation from custard apple seeds in 2000. One of the proposed structures, benzo[f]phthalazin-4(3H)-one, was prepared in two steps by regioselective ortho-lithiation/formylation of N,N-diisopropyl-2-naphthylamide, followed by cyclization with hydrazine, but was shown to be different from the natural product. Perlolidine, another candidate structure, was synthesized by a novel route involving a β-selective Heck reaction of butyl vinyl ether. Both perlolidine and samoquasine A are converted by trimethylsilyldiazomethane into the same N-methyl derivative. In addition, the 13C NMR spectra of perlolidine and another structurally mis-assigned natural product, cherimoline, are almost identical. Thus, both samoquasine A and cherimoline are actually perlolidine.

Synthesis of the grass alkaloid perlolidine through a pyridyne cyclisation reaction

A synthesis of the grass alkaloid perlolidine is described in which the key step involves the pyridyne cyclisation of 2-benzyloxy-5-bromo-3-[(N-phenyl) aminomethyl] pyridine.

Synthesis of various substituted benzo[c]-2,7-naphthyridines and an approach towards the skeleton of meridine. Considerations about the effect of copper (II)oxide

Derivatives of benzo[c]-2,7-naphthyridines have been prepared in good yields and in one step through the use of the Pd(0)-catalyzed cross couplings of 4-formyl- and 4-acetyl-3-pyridyltrimethylstannanes with ortho-bromoacetanilides. Perlolidine, an alkaloi

First Metalation of Aryl Iodides: Directed Ortho-Lithiation of Iodopyridines, Halogen-Dance, and Application to Synthesis

Metalation of iodopyridines was succesfully achieved by LDA at low temperature.In many cases, lithiation is ortho directed by the iodo group which subsequently ortho-migrates very fast to give stabilized iodolithiopyridines.This procedure was applied to 2