73441-60-8

Basic information

• Product Name: (4-(allyloxy)phenyl)(methyl)sulfane
• Synonyms: (4-(allyloxy)phenyl)(methyl)sulfane
• CAS NO: 73441-60-8
• Molecular Weight: 180.271
• Mol File: 73441-60-8.mol

Chemical Properties

• CAS DataBase Reference: (4-(allyloxy)phenyl)(methyl)sulfane(CAS DataBase Reference)
• NIST Chemistry Reference: (4-(allyloxy)phenyl)(methyl)sulfane(73441-60-8)
• EPA Substance Registry System: (4-(allyloxy)phenyl)(methyl)sulfane(73441-60-8)

Safety Data

• Hazardous Substances Data: 73441-60-8(Hazardous Substances Data)

Upstream product

• 1073-72-9 4-hydroxythioanisole 
• 106-95-6 allyl bromide 
• 637-89-8 4-sulfanylphenol 

Downstream Products

• 58090-28-1 1-(4-methylsulfonylphenoxy)-2,3-epoxypropane 
• 99186-51-3 1-(allyloxy)-4-(methylsulfonyl)benzene 
• 1415236-88-2 2-(4-(allyloxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1073-72-9 4-hydroxythioanisole 
• 1365640-43-2 2-allyl-4-(methylsulfanyl)phenyl propionate 
• 73441-61-9 2-Allyl-4-methylsulfanyl-1-(4-nitro-phenoxy)-benzene 
• 73255-11-5 2-allyl-4-(methylsulfanyl)phenol 

Relevant articles and documents

Nickel Hydride Catalyzed Cleavage of Allyl Ethers Induced by Isomerization

This report discloses the deallylation of O - and N -allyl functional groups by using a combination of a Ni-H precatalyst and excess Bronsted acid. Key steps are the isomerization of the O - or N -allyl group through Ni-catalyzed double-bond migration followed by Bronsted acid induced O/N-C bond hydrolysis. A variety of functional groups are tolerated in this protocol, highlighting its synthetic value.

Ether aryl sulfonic acid esters with improved antimalarial/anticancer activities

Our previous report showed that our current benchmark agent, 4-methoxyphenyl p-toluenesulibnate, is a selective antimalarial/anticancer agent. A series of related sulfones and sulfonic acid esters is now examined. 4-Allyloxyphenyl p-toluenesulfonate is a superior antimalarial/anticancer agent. 4-Methoxyphenyl 4-nitrobenzenesulfonate is a superior antimalarial agent, but shows poorer inhibition of human skin cancer cells. CSIRO 2006.

Thermodynamic, spectroscopic, and density functional theory studies of allyl aryl and prop-1-enyl aryl ethers. Part 1. Thermodynamic data of isomerization

A chemical equilibration study of the relative thermodynamic stabilities of seventy isomeric allyl aryl ethers (a) and (Z)-prop-1-enyl aryl ethers (b) in DMSO solution has been carried out. From the variation of the equilibrium constant with temperature the Gibbs energies, enthalpies, and entropies of isomerization at 298.15 K have been evaluated. Because of their low enthalpies, the (Z)-prop-1-enyl aryl ethers are strongly favored at equilibrium, the Gibbs energies of the a→b isomerization ranging from -12 to -23 kJ mol-1. The entropy contribution is negligible in most reactions, but occasionally small positive values less than +10 J K-1 mol-1 of the entropy of isomerization are found. The equilibration studies were also extended to involve two pairs of related isomeric ethers with a Me substituent on C(2) of the olefinic bond. The Me substituent was found to increase the relative thermodynamic stability of the allylic ethers by ca. 3.4 kJ mol-1.