73469-31-5

Upstream product

• 122-01-0 4-chloro-benzoyl chloride 
• 73425-25-9 4-(N-tert-butoxycarbonyl-N-methylaminomethyl)-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole 
• 73425-49-7 4-aminomethyl-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole 

Relevant academic research and scientific papers

Tetrahydrothiopyrano[2,3-b]indole derivatives

Tetrahydrothiopyrano[2,3-b]indole derivative represented by the formula I: STR1 wherein R1 is hydrogen, alkyl, hydroxyalkyl, alkenyl, aralkyl, aryl, --COR5 (wherein R5 is alkyl, alkenyl, aryl or alkoxy) or STR2 (wherein Y is alkylene, oxoalkylene, hydroxyalkylene and R6 and R7 are each hydrogen or alkyl): R2 is hydrogen or alkyl; R3 is hydrogen, alkyl, hydroxyalkyl, alkenyl, aralkyl, aryl or dialkylaminoalkyl or STR3 is pyrrolidino, piperidino, piperazino, 4-alkylpiperazino, 4-arylpiperazino or morpholino; R4 is hydrogen or alkyl; A is methylene, alkylmethylene, ethylene, alkylethylene; X is hydrogen or one or two groups selected from the group consisting of halogen, alkyl, alkoxy, hydroxy and halogenoalkyl; and n is an integer of 0 to 2 and its pharmaceutically acceptacle salts; synthesized from 2-propargylthioindole or 2-(4-hydroxy-2-butynylthio)-indole; useful as analgesic and anti-inflammatory agent.