73492-25-8

Usage

Uses

Used in Chemical Synthesis:
1-chloro-1-chloro-acetyl-cyclopropane is used as a chemical intermediate for the synthesis of various organic compounds. Its reactivity, due to the presence of multiple chloro groups, allows it to participate in a range of chemical reactions, making it a valuable component in the production of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Industrial Processes:
1-chloro-1-chloro-acetyl-cyclopropane is used as a reactant in certain industrial processes. Its unique structure and reactivity enable it to be employed in the manufacturing of specific materials or products, where its chemical properties can be harnessed to achieve desired outcomes.
Used in Research and Development:
1-chloro-1-chloro-acetyl-cyclopropane is used as a research compound for studying the properties and behavior of organochlorine compounds. Its complex structure and potential for chemical transformations make it an interesting subject for scientific investigation, which could lead to new insights and applications in the field of organic chemistry.

Upstream product

• 4023-34-1 cyclopropanecarboxylic acid chloride 
• 108817-35-2 1-chlorocyclopropane-1-carboxylic acid 

Downstream Products

• 70339-21-8 4'-(isopropoxy)-3'-(trifluoromethyl)-1-chlorocyclopropanecarboxanilide 
• 139297-65-7 1-(1-chlorocyclopropyl)-2-(2-chlorophenyl)ethanone 

Relevant academic research and scientific papers

Novel bi-cyclic or tri-cyclic heterocyclic compound

The present invention provides novel bi-cyclic or tri-cyclic compound represented by formula (I) or pharmaceutical acceptable salt thereof, [wherein, ring A is an aromatic group which may be substituted, one of X1 and X2 is a carbon atom, and another is a nitrogen atom, X3 is a nitrogen atom or CR2, X4 is a nitrogen atom or CR3, X5 is a sulfur atom or -CH=CH-, Z1 is an oxygen atom, -C(R6)(R7)-, -NH-, -C(R6)(R7)-NH-, -NH-C(R6)(R7)-, -C(R6)(R7)-O-, -O-C(R6)(R7)- or a single bone, one of Z2 and Z3 is CH and another one is a nitrogen atom, or both are nitrogen atoms, the other symbols are same as those defined in the specification.]

Kinetics of Cyclopropyl Radical Reactions. 3. Study of Some 1-Substituted Cyclopropyl Radicals by EPR Spectroscopy. The Inversion Barrier for 1-Methylcyclopropyl

The 1-methyl-, 1-ethoxy-, and 1-chlorocyclopropyl radicals have been observed by low-temperature EPR spectroscopy in "frozen" configurations in which the ring hydrogens that are syn and anti to the unpaired elecron's orbital have different hyperfine splittings.The aH(syn)/aH(anti) ratios are 1.5 (CH3), 1.8 (EtO), and 1.9 (Cl), all considerably lower than the ratio of ca. 3.3 found by Kawamura et al. for methyl-substituted 1-fluorocyclopropyl radicals.The out-of-plane angles of the 1-substituent have been calculated from measured a13Cα values to be 22.5 deg (cyclopropyl), 22.9 deg (CH3), 29.1 deg (EtO), and 5.8 deg (MeSi).These angles are considerably smaller than those that have been calculated for some of these radicals by ab initio and other methods.Variable-temperature EPR spectroscopy on 1-methylcyclopropyl yields the following Arrhenius equation for its inversion: log (kinv/s-1) = (13.1 +/- 0.3) - (3.1 +/- 0.2)/2.3RT kcal/mol.For 1-ethoxycyclopropyl the rate constant for rotation about the .C-OEt bond can be represented by log (krot/s-1) = (12.5 +/- 0.2) - (5.8 +/- 0.2)/2.3RT.The barrier to inversion of this radical is >/= 9 kcal/mol.The 1-chlorocyclopropyl radical could only be observed at very low temperatures.