73493-56-8

Basic information

• Product Name: sodium (2R)-<2-²H₁>propanoate
• Synonyms: sodium (2R)-<2-²H₁>propanoate
• CAS NO: 73493-56-8
• Molecular Weight: 97.0533
• Mol File: 73493-56-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: sodium (2R)-<2-²H₁>propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: sodium (2R)-<2-²H₁>propanoate(73493-56-8)
• EPA Substance Registry System: sodium (2R)-<2-²H₁>propanoate(73493-56-8)

Safety Data

• Hazardous Substances Data: 73493-56-8(Hazardous Substances Data)

Upstream product

• 57057-80-4 ethyl (S)-2-[[(4-methylphenyl)sulfonyl]oxy]propanoate 
• 32644-15-8 (S)-2-bromopropanoic acid 

Downstream Products

• 133665-56-2 (2R,2'S)-2-(1-oxopropoxy-2-d)-2-phenylacetic acid methyl ester 

Relevant articles and documents

Stereochemistry of hydrogen loss on formation of the vinyl group in the biosynthesis of ravidomycin

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Characterisation of the citrate synthase reaction with propionyl-CoA.

Experiments with propionyl-CoA stereoselectively deuteriated in the propionyl moiety demonstrate that the formation of (2S,3S)-methylcitric acid (1) catalysed by citrate (si)-synthase occurs with inversion of configuration in the propionyl moiety; the absolute configurations of the methylcitric acids 1 and 2 indicate a si attack on oxaloacetate. Deuterium in the pro-S position is exchanged for protium 60 times faster than deuterium in the pro-R position. Experiments with (R,S)-(2-2H1)propionyl-CoA allowed the determination of isotope effects. For the enzymatic formation of 1, a primary deuterium isotope effect kH/kD = 1.8 and a secondary alpha-deuterium isotope effect kH/kD = 0.99 were calculated; both are effects on Vmax/KM.