73494-01-6

Upstream product

• 162132-42-5 (Z)-1-acetoxy-3-(4-methyl-3-cyclohexen-1-yl)-2-butene 
• 70286-15-6 methyl (Z)-3-(4-methyl-3-cyclohexen-1-yl)-2-butenoate 
• 162132-41-4 methyl 3-(4-methyl-3-cyclohexen-1-yl)propynoate 
• 162132-39-0 1,1-dibromo-2-(4-methyl-3-cyclohexen-1-yl)ethene 
• 4342-60-3 4-methylcyclohex-3-enecarboxylic acid 
• 7560-64-7 4-methyl-cyclohex-3-enecarbaldehyde 
• 39155-38-9 (4-methylcyclohex-3-en-1-yl)methanol 
• 70240-37-8 (Z)-3-(4-methyl-3-cyclohexen-1-yl)-2-buten-1-ol 

Downstream Products

• 29837-07-8 (Z)-α-bisabolene 
• 25532-79-0 (E)‐α‐bisabolene 
• 120657-79-6 methyl 4-(4'-methylcyclohex-3'-en-1-yl)pent-3-enoate 
• 120657-81-0 4-(4'-methylcyclohex-3'-en-1-yl)pent-3-en-1-al 
• 120657-80-9 4-(4'-methylcyclohex-3'-en-1-yl)pent-3-enol 
• 120657-78-5 3-(4'-methylcyclohex-3'-en-1-yl)but-2-enyl cyanide 

Relevant academic research and scientific papers

Termite trail attractants: New synthesis of racemic (E)-α-, (Z)-α- and β-bisabolenes

Racemic (E)-α-bisabolene (E)(1) was synthetized starting from 4-methyl-3-cyclohexenecarboxylic acid (3) by a reaction sequence involving the Pd(0)-catalyzed cross-coupling reaction between the (E)-2-methyl-1-alkenyltrimethylstannane 8 and 3-methyl-2-buten-1-yl acetate (9). Three different procedures, in which a common precursor was used as key intermediate, were tested for the synthesis of racemic (Z)-α-bisabolene (Z)(1). The best one, which involved the reaction between bromide 18 and lithium dialkenylcuprate 19, afforded a mixture of (Z)- and (E)-1 in a 93:7 molar ratio, respectively. Finally, racemic β-bisabolene (2) was synthetized by a simple reaction sequence involving the Zr-promoted methylenation of ketone 22 prepared from 3.