4342-60-3Relevant academic research and scientific papers
TWO CONVENIENT METHODS FOR THE GENERATION OF "METHYLENE MELDRUM'S ACID" FOR DIELS- ALDER REACTIONS.
Buzinkai, John F.,Hrubowchak, David M.,Smith, Francis X.
, p. 3195 - 3198 (1985)
The transient isopropylidene methylenemalonate can be easily generated by treating either Meldrum's acid or diisopropylidene methylenedimalonate with formaldehyde, and trapped by reactive dienes.
CANNABINOID DERIVATIVES, PRECURSORS AND USES
-
, (2021/03/19)
The present disclosure relates to new cannabinoid derivatives and precursors and processes for their preparation. The disclosure also relates to pharmaceutical and analytical uses of the new cannabinoid derivatives.
BORON-BASED CYCLOADDITION CATALYSTS AND METHODS FOR THE PRODUCTION OF BIO-BASED TEREPHTHALIC ACID, ISOPHTHALIC ACID AND POLY (ETHYLENE TEREPHTHALATE)
-
Paragraph 00172; 00173, (2017/04/11)
Methods for producing cycloaddition products comprising: reacting a diene with a dienophile in the presence of one or more boron-based catalysts of Formula I or Formula II are provided. In particular, the methods can be used to prepare 4-methyl-3-cyclohexene- 1-carboxylic acid and 3-methyl-3-cyclohexene-l-carboxylic acid, including bio-based versions thereof. The cycloaddition products can be advantageously used in the production of terephthalic acid and isophthalic acid, and ultimately, poly(ethylene terephthalate), and bio-based versions thereof. Formula I Formula II
METHODS OF SYNTHESIS OF (1R,2R,5R)-5-AMINO-2-METHYLCYCLOHEXANOL HYDROCHLORIDE AND INTERMEDIATES USEFUL THEREIN
-
, (2017/02/24)
Provided herein are methods and intermediates for making (lR,2R,5R)-5-amino-2- methylcyclohexanol hydrochloride, which are useful for the preparation of compounds useful for the treatment of a disease, disorder, or condition associated with the JNK pathwa
Method for preparation of 4-methylcyclohex-3-ene-1-carboxylic acid from 4-methyl-3-cyclohexene-1-carbaldehyde
-
Paragraph 0022, (2017/04/25)
The invention relates to a method for preparation of 4-methylcyclohex-3-ene-1-carboxylic acid by selective oxidation of 4-methyl-3-cyclohexene-1-carbaldehyde. Specifically, the method includes: under an alkaline condition, under the action of a supported
Polyelectrolyte-catalyzed Diels–Alder reactions
Pothanagandhi, Nellepalli,Sivaramakrishna, Akella,Vijayakrishna, Kari
, p. 132 - 136 (2016/08/05)
Imidazolium-based poly(ionic liquids) bearing bromide and bis(trifluoromethane)sulfonimide as counteranions [poly(ViEIm)Br and poly(ViEIm)NTf2] derived from reversible addition fragmentation chain transfer (RAFT) polymerization techniques are u
Synthesis of 1,3-Cycloalkadienes from Cycloalkenes: Unprecedented Reactivity of Oxoammonium Salts
Nagasawa, Shota,Sasano, Yusuke,Iwabuchi, Yoshiharu
supporting information, p. 13189 - 13194 (2016/10/30)
Few methods allow for the direct conversion of cycloalkenes into cycloalkadienes with high chemo- and regioselectivity. Herein, we report a convenient one-pot process for this transformation that involves the unprecedented N-preferential group transfer of N-oxoammonium salts to cycloalkenes, followed by Cope elimination, to afford cycloalkadienes at room temperature and pressure.
NOVEL COMPOUNDS
-
Page/Page column 28, (2015/02/02)
Novel rapamycin analogues and methods for their production with FKBP and/or MIP inhibitory activity with reduced mTOR inhibitory activity with therapeutic potential e.g. as bacterial virulence inhibitors.
SOLID FORMS OF 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRIMIDINE-5-CARBOXAMIDE, COMPOSITIONS THEREOF AND METHODS OF THEIR USE
-
Paragraph 00458, (2015/11/02)
Provided herein are formulations, processes, solid forms and methods of use relating to 2- (tert-butylamino)-4-((lR,3R,4R)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5- carboxamide.
Dehydro-aromatization of cyclohexene-carboxylic acids by sulfuric acid: Critical route for bio-based terephthalic acid synthesis
Wang, Fei,Tong, Zhaohui
, p. 6314 - 6317 (2014/01/23)
A novel dehydro-aromatization reaction under mild reaction conditions was successfully developed using sulfuric acid as a cost-effective and efficient oxidant. This reaction simplified the synthesis of terephthalic acid (TA, an important aromatic monomer precursor) from biomass-derived isoprene and acrylic acid.
