4342-60-3Relevant academic research and scientific papers
TWO CONVENIENT METHODS FOR THE GENERATION OF "METHYLENE MELDRUM'S ACID" FOR DIELS- ALDER REACTIONS.
Buzinkai, John F.,Hrubowchak, David M.,Smith, Francis X.
, p. 3195 - 3198 (1985)
The transient isopropylidene methylenemalonate can be easily generated by treating either Meldrum's acid or diisopropylidene methylenedimalonate with formaldehyde, and trapped by reactive dienes.
CANNABINOID DERIVATIVES, PRECURSORS AND USES
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, (2021/03/19)
The present disclosure relates to new cannabinoid derivatives and precursors and processes for their preparation. The disclosure also relates to pharmaceutical and analytical uses of the new cannabinoid derivatives.
METHODS OF SYNTHESIS OF (1R,2R,5R)-5-AMINO-2-METHYLCYCLOHEXANOL HYDROCHLORIDE AND INTERMEDIATES USEFUL THEREIN
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, (2017/02/24)
Provided herein are methods and intermediates for making (lR,2R,5R)-5-amino-2- methylcyclohexanol hydrochloride, which are useful for the preparation of compounds useful for the treatment of a disease, disorder, or condition associated with the JNK pathwa
BORON-BASED CYCLOADDITION CATALYSTS AND METHODS FOR THE PRODUCTION OF BIO-BASED TEREPHTHALIC ACID, ISOPHTHALIC ACID AND POLY (ETHYLENE TEREPHTHALATE)
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Paragraph 00172; 00173, (2017/04/11)
Methods for producing cycloaddition products comprising: reacting a diene with a dienophile in the presence of one or more boron-based catalysts of Formula I or Formula II are provided. In particular, the methods can be used to prepare 4-methyl-3-cyclohexene- 1-carboxylic acid and 3-methyl-3-cyclohexene-l-carboxylic acid, including bio-based versions thereof. The cycloaddition products can be advantageously used in the production of terephthalic acid and isophthalic acid, and ultimately, poly(ethylene terephthalate), and bio-based versions thereof. Formula I Formula II
Method for preparation of 4-methylcyclohex-3-ene-1-carboxylic acid from 4-methyl-3-cyclohexene-1-carbaldehyde
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Paragraph 0022, (2017/04/25)
The invention relates to a method for preparation of 4-methylcyclohex-3-ene-1-carboxylic acid by selective oxidation of 4-methyl-3-cyclohexene-1-carbaldehyde. Specifically, the method includes: under an alkaline condition, under the action of a supported
Polyelectrolyte-catalyzed Diels–Alder reactions
Pothanagandhi, Nellepalli,Sivaramakrishna, Akella,Vijayakrishna, Kari
, p. 132 - 136 (2016/08/05)
Imidazolium-based poly(ionic liquids) bearing bromide and bis(trifluoromethane)sulfonimide as counteranions [poly(ViEIm)Br and poly(ViEIm)NTf2] derived from reversible addition fragmentation chain transfer (RAFT) polymerization techniques are u
Synthesis of 1,3-Cycloalkadienes from Cycloalkenes: Unprecedented Reactivity of Oxoammonium Salts
Nagasawa, Shota,Sasano, Yusuke,Iwabuchi, Yoshiharu
supporting information, p. 13189 - 13194 (2016/10/30)
Few methods allow for the direct conversion of cycloalkenes into cycloalkadienes with high chemo- and regioselectivity. Herein, we report a convenient one-pot process for this transformation that involves the unprecedented N-preferential group transfer of N-oxoammonium salts to cycloalkenes, followed by Cope elimination, to afford cycloalkadienes at room temperature and pressure.
NOVEL COMPOUNDS
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Page/Page column 28, (2015/02/02)
Novel rapamycin analogues and methods for their production with FKBP and/or MIP inhibitory activity with reduced mTOR inhibitory activity with therapeutic potential e.g. as bacterial virulence inhibitors.
SOLID FORMS OF 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRIMIDINE-5-CARBOXAMIDE, COMPOSITIONS THEREOF AND METHODS OF THEIR USE
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Paragraph 00458, (2015/11/02)
Provided herein are formulations, processes, solid forms and methods of use relating to 2- (tert-butylamino)-4-((lR,3R,4R)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5- carboxamide.
Dehydro-aromatization of cyclohexene-carboxylic acids by sulfuric acid: Critical route for bio-based terephthalic acid synthesis
Wang, Fei,Tong, Zhaohui
, p. 6314 - 6317 (2014/01/23)
A novel dehydro-aromatization reaction under mild reaction conditions was successfully developed using sulfuric acid as a cost-effective and efficient oxidant. This reaction simplified the synthesis of terephthalic acid (TA, an important aromatic monomer precursor) from biomass-derived isoprene and acrylic acid.
