73496-36-3

Upstream product

• 26607-51-2 N-benzyloxycarbonyl-D-alanine 
• 73496-35-2 7-(N^α-Boc-L-Leucyl-N^ε-Z-L-lysinamido)-4-(trifluoromethyl)coumarin 
• 591-27-5 m-Hydroxyaniline 
• 53518-15-3 Coumarin 151 
• 2389-45-9 Boc-Lys(Z)-OH 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 

Relevant academic research and scientific papers

Synthesis and Chemistry of 7-Amino-4-(trifluoromethyl)coumarin and Its Amino Acid and Peptide Derivatives

The synthesis and purification of 7-amino-4-(trifluoromethyl)coumarin, a novel fluorescent marker for the sensitive detection of proteinases, were investigated.Two byproducts, 7-hydroxy-4-(trifluoromethyl-2-quinolone and 2-ethoxy-7-hydroxy-4-(trifluoromethyl)quinoline, were isolated and identified. 7-Methoxy-4-(trifluoromethyl)-2-quinolone was also prepared.Amino acid and peptide derivatives prepared by solution methods using the stepwise approach included 7-(L-leucinamido)-, 7-(D-alanyl-L-leucyl-L-lysinamido)-, 7-(D-valyl-L-leucyl-L-lysinamido)-, and 7-(Nα-Z-glycylglycyl-L-argininamido)-4-(trifluoromethyl)coumarins