73515-02-3

Basic information

• Product Name: ethyl 4-{[6-(diethoxyphosphoryl)hexyl]oxy}benzoate
• Synonyms: benzoic acid, 4-[[6-(diethoxyphosphinyl)hexyl]oxy]-, ethyl ester
• CAS NO: 73515-02-3
• Molecular Formula: C₁₉H₃₁O₆P
• Molecular Weight: 386.4196
• Mol File: 73515-02-3.mol

Chemical Properties

• Boiling Point: 497.4°C at 760 mmHg
• Flash Point: 267.8°C
• Density: 1.093g/cm³
• Vapor Pressure: 4.95E-10mmHg at 25°C
• Refractive Index: 1.485
• CAS DataBase Reference: ethyl 4-{[6-(diethoxyphosphoryl)hexyl]oxy}benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-{[6-(diethoxyphosphoryl)hexyl]oxy}benzoate(73515-02-3)
• EPA Substance Registry System: ethyl 4-{[6-(diethoxyphosphoryl)hexyl]oxy}benzoate(73515-02-3)

Safety Data

• Hazardous Substances Data: 73515-02-3(Hazardous Substances Data)

Upstream product

• 73515-07-8 6-(4-carbethoxyphenoxy)hexyl bromide 
• 122-52-1 triethyl phosphite 

Relevant articles and documents

Synthesis of Some Phosphonates with Antiherpetic Activity

Several keto phosphonates, phosphonoacetates, and dialkyl phosphonates containing (aryloxy)aryl group were synthesized and evaluated for antiherpetic activity.Two of the most active compounds, 12 and 16, were evaluated topically in the mouse vaginal model against herpes simplex virus (HSV) type 2.Compound 16 exhibited an increased survival rate, as well as increased survival time.Evaluation of 16 in the guinea pig skin test against HSV-2 produced a reduction in virus titer, as well as in mean vesicle score.

Arylalkyl and aryloxyalkyl phosphonates and use as antiviral agents

Arylalkyl and aryloxyalkylphosphonates, useful as antiviral agents, are prepared by reacting an arylalkyl or aryloxyalkyl halide with a trialkyl phosphite, or with an alkali metal salt of a dialkyl phosphonate, trialkyl phosphonoalkanoate or dialkyl phosphonoalkanone.