73519-41-2Relevant academic research and scientific papers
Self-assembly of small peptidomimetic cyclophanes
Becerril, Jorge,Burguete, M. Isabel,Escuder, Beatriu,Galindo, Francisco,Gavara, Raquel,Miravet, Juan F.,Luis, Santiago V.,Peris, Gabriel
, p. 3879 - 3890 (2007/10/03)
The self-assembly of a series of small peptidomimetic cyclophanes in organic solvents was studied. X-ray diffraction, NMR spectroscopy, and molecular modelling were used to understand the structural features of these self-assembling compounds both at the molecular and supramolecular level. The factors that could influence the formation of gels rather than crystals were studied and a model for the arrangement of molecules in the gel was proposed. Furthermore, scanning electron microscopy revealed that in some cases these compounds undergo a transcription of chirality when going from organogelator to helicoidal gel fibres.
Photochemistry of dipeptides in aqueous solution
Hill, Roger R.,Coyle, John D.,Birch, David,Dawe, Edwin,Jeffs, Graham E.,Randall, David,Stec, Iwan,Stevenson, Tessa M.
, p. 1805 - 1817 (2007/10/02)
The photochemical lability of peptides is poorly understood, largely because of the lack of product data. In the present study, product analyses have been carried out following the photolyses in aqueous solution of selected glycyl dipeptides (Gly-Gly, DL-Ala-Gly, L-Val-Gly, L-Pro-Gly, L-Phe-Gly, and Gly-L-Phe), L-prolyl-L-phenylalanine, and L-phenylalanyl-L-proline. Efficient deamination and decarboxylation of aliphatic dipeptides generate thermal precursors of simple amides in a photoinduced electron-transfer process involving the peptide bond. An analogous pathway in the photodegradation of phenylalanyl peptides suffers competition from other types of reaction.
Studies on 2-Aziridinecarboxylic Acid.III. Reaction of 1-Acyl-2-aziridinecarboxylic Acid Peptide with Amines
Nakajima, Kiichiro,Tanaka, Takumi,Morita, Kaoru,Okawa, Kenji
, p. 283 - 284 (2007/10/02)
The reaction of Z-Gly-Azy-Gly-OBzl with amines was studied.With primary amines, the 1-acyl group (Z-Gly) of the aziridine peptide mainly migrated to the reactant amine with cleaving of the amide bond between glycine and aziridine, whereas aniline and diethylamine gave diaminopropionic acid derivatives via the ring opening reaction.
