73522-42-6

Basic information

• Product Name: (-)-CIS-MYRTANYLAMINE
• Synonyms: (-)-cis-Myrtanylamine;Bicyclo[3.1.1]heptane-2-methanamine, 6,6-dimethyl-, (1S,2R,5S)-
• CAS NO: 73522-42-6
• Molecular Formula: C₁₀H₁₉N
• Molecular Weight: 153.26
• Mol File: 73522-42-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 266.22°C (rough estimate)
• Flash Point: 78°C
• Appearance: /
• Density: 0.9327
• Refractive Index: 1.4877
• PKA: 10.20±0.29(Predicted)
• CAS DataBase Reference: (-)-CIS-MYRTANYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-CIS-MYRTANYLAMINE(73522-42-6)
• EPA Substance Registry System: (-)-CIS-MYRTANYLAMINE(73522-42-6)

Safety Data

• RIDADR: UN 2735PSN1 8 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 73522-42-6(Hazardous Substances Data)

Usage

Description

(-)-CIS-MYRTANYLAMINE is an organic compound that serves as a versatile building block and reactant in various chemical synthesis processes. It is characterized by its unique structure and properties, making it a valuable component in the development of new chemical compounds and materials.

Uses

Used in Chemical Synthesis:
(-)-CIS-MYRTANYLAMINE is used as a reactant for the preparation of N,N-bis((-)-cis-myrtanyl)butylene-2,3-diimine (BMDI), a bidentate diimine ligand. This ligand is capable of forming transition metal complexes, which are utilized as catalysts in asymmetric synthesis, a crucial technique in the production of enantiomerically pure compounds.
Used in Pharmaceutical Industry:
(-)-CIS-MYRTANYLAMINE is used as a building block to prepare imidazole derivatives. These derivatives have been found to be potent and selective cannabinoid receptor (CB2) antagonists. CB2 antagonists have potential therapeutic applications in various diseases, including inflammation and pain, making (-)-CIS-MYRTANYLAMINE a valuable component in the development of new pharmaceuticals.
Used in Catalyst Development:
(-)-CIS-MYRTANYLAMINE can be used to prepare a chiral catalyst for asymmetric three-component Mannich reaction. This reaction is an important carbon-carbon bond-forming process in organic synthesis, and the development of efficient and enantioselective catalysts is crucial for the synthesis of biologically active molecules and pharmaceuticals.

Upstream product

• 177698-19-0 Beta-pinene 

Downstream Products

• 1240974-25-7 N-myrtanyl-5-methyl-1-(2',4'-dichlorophenyl)-1,4-dihydro-thieno[3',2':4,5]cyclopenta[1,2-c]pyrazol-3-carboxamide 
• 1240974-10-0 N-myrtanyl-6-methyl-1-(4'-methylbenzyl)-1,4-dihydrothieno[3',2':4,5]cyclopenta[1,2-c]pyrazol-3-carboxamide 
• 252900-45-1 2-(((1S,2R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-yl)methyl)isoindole-1,3-dione 
• 780790-79-6 3-(4-chloro-6-(((1S,2R,5S)-6,6-dimethylbicyclo[3.1.1]heptan-2-yl)methylamino)-1,3,5-triazin-2-ylamino)-4-methylbenzamide 
• 28272-96-0 2-vinylbenzaldehyde