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(9S)-10,11-dihydro-Cinchonan-6',9-diol is a chemical compound that belongs to the class of organic compounds known as cinchona alkaloids. It is derived from the natural cinchona tree and exhibits a dihydro-Cinchonan-6',9-diol structure. (9S)10,11-dihydro-Cinchonan-6',9-diol has been used in the synthesis of various pharmaceuticals and is known for its anti-malarial properties. Its chemical structure and properties make it a valuable compound in medicinal chemistry and organic synthesis, as it serves as a starting material for the preparation of numerous bioactive molecules. Its potential as an anti-malarial agent makes it an important compound for further research and development in the field of medicinal chemistry.

73522-75-5

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73522-75-5 Usage

Uses

Used in Pharmaceutical Industry:
(9S)-10,11-dihydro-Cinchonan-6',9-diol is used as a key intermediate in the synthesis of various pharmaceuticals for its versatile chemical structure and properties. It serves as a starting material for the preparation of numerous bioactive molecules, making it a valuable compound in medicinal chemistry.
Used in Antimalarial Drug Development:
(9S)-10,11-dihydro-Cinchonan-6',9-diol is used as an anti-malarial agent for its potential to treat malaria, a life-threatening disease caused by Plasmodium parasites. Its anti-malarial properties make it an important compound for further research and development in the field of medicinal chemistry, with the aim of discovering new and effective treatments for this devastating disease.

Check Digit Verification of cas no

The CAS Registry Mumber 73522-75-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,5,2 and 2 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 73522-75:
(7*7)+(6*3)+(5*5)+(4*2)+(3*2)+(2*7)+(1*5)=125
125 % 10 = 5
So 73522-75-5 is a valid CAS Registry Number.

73522-75-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (3R,8R,9S)-10,11-dihydro-3,6'-dihydroxycinchonane

1.2 Other means of identification

Product number -
Other names dihydrocupreidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:73522-75-5 SDS

73522-75-5Relevant academic research and scientific papers

Expansion of the aromatic part of Cinchona alkaloids. Annulation of quinolines with phenoxazine motifs

W?sińska-Ka?wa, Ma?gorzata,Giurg, Miros?aw,Boratyński, Przemys?aw J.,Skar?ewski, Jacek

, p. 308 - 315 (2017/12/08)

An oxidative cross-coupling strategy for quinoline ring annulation in Cinchona alkaloids has been developed. Key-reaction optimization by changing oxidants and adjusting the nucleophilicity of the 2-aminophenols led to cupreine and cupreidine expanded with the phenoxazinone unit in 56–75% yield. The stereochemical integrity of the obtained alkaloid structures was confirmed by combined experimental and computed CD and NMR data. The conformational study revealed a fast equilibrium of the three conformers, differing in the orientation of the pyrido[a-3,2]phenoxazine moiety.

β-Isocupreidine-hexafluoroisopropyl acrylate method for asymmetric Baylis-Hillman reactions

Nakano, Ayako,Kawahara, Sakie,Akamatsu, Saori,Morokuma, Kenji,Nakatani, Mari,Iwabuchi, Yoshiharu,Takahashi, Keisuke,Ishihara, Jun,Hatakeyama, Susumi

, p. 381 - 389 (2007/10/03)

Key features of the β-isocupreidine (β-ICD)-catalyzed asymmetric Baylis-Hillman reaction of aldehydes with 1,1,1,3,3,3-hexafluoroisopropyl acrylate (HFIPA) are presented. In addition, an improved method using azeotropically dried β-ICD is described.

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