735240-08-1

Upstream product

• 103-67-3 benzyl-methyl-amine 
• 939-52-6 4-chloro-1-phenylbutan-1-one 
• 65488-05-3 4-iodobutyrophenone 

Downstream Products

• 947373-08-2 4-(N-benzyl-N-methylamino)-1-phenylbutan-1-ol 

Relevant academic research and scientific papers

Efficient asymmetric hydrogenation of β- and γ-amino ketone derivatives leading to practical synthesis of fluoxetine and eprozinol

N-(Methylcarbamoyl)-4-(dicyclohexylphosphino)-2-[(diphenylphosphino)me thyl]pyrrolidine (MCCPM)- and N-(tert-butoxycarbonyl)-4-(dicyclohexylphosphino)-2-[(diphenylphosphin o)methyl]pyrrolidine (BCPM)-rhodium(I) complexes were efficient catalysts for asymmetric hydrogenations of β- and γ-amino ketone hydrochloride derivatives. Utilizing this methodology, we have developed efficient syntheses of fluoxetine and eprozinol from intermediate optically active amino alcohols.

NOVEL CENTRAL-NERVOUS SYSTEM ACTING COMPOUNDS AND METHODS FOR THE TREATMENT OF CNS DISORDERS

This application relates to a new class of butylamine compounds useful as balanced serotonin/dopamine uptake inhibitors for treating a disease or condition for which inhibition of both serotonin and dopamine reuptake is beneficial, for example, depression