73544-56-6

Upstream product

• 72584-12-4 p-Nitrobenzyl (5R,6R)-3-(2-acetamidoethylthio)-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 73521-63-8 p-nitrobenzyl (5R)-3-(2-acetamidoethylthio)-6-(E)-ethylidene-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 
• 71730-34-2 p-Nitrobenzyl (5R,6R)-3-(2-acetamidoethylthio)-6-ethyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate 
• 77058-03-8 (5R,6S)-3-(2-Acetylamino-ethylsulfanyl)-6-ethyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 67007-79-8 PS-5 

Relevant academic research and scientific papers

Carbapenum derivatives, a process for their preparation and their use in pharmaceutical compositions and intermediates

The present invention provides antibiotic compounds of the formula: STR1 and salts and cleavable esters thereof wherein X is a SCH2 CH2 NH2 or YNH-COCH3 group where Y is a SCH2 CH2, trans -

Conversion of the Olivanic Acids into Antibiotics of the PS-5 Type: Use of a New Carboxy Protecting Group

The syntheses of PS-5 (1) and analogues from the olivanic acids MM 17880 (4) and MM 13902 (10), including the use of a new carboxy protecting group, the p-methoxycarbonylbenzyl group, are reported together with the chemical elucidation of the stereochemis