73576-32-6 Usage
General Description
2-Amino-4-hydroxy-6-isopropylpyrimidine, also known as AIP, is a chemical compound that is commonly used in the pharmaceutical industry. It is a pyrimidine derivative with a molecular formula of C7H10N4O and a molecular weight of 166.18 g/mol. AIP is known for its anti-cancer properties and has been studied for its potential use in cancer therapy. It is also used as a building block in the synthesis of various pharmaceutical compounds. AIP has also been investigated for its potential role in the treatment of neurological disorders and as an antiviral agent. Overall, 2-Amino-4-hydroxy-6-isopropylpyrimidine has a wide range of potential applications in the field of medicine and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 73576-32-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,5,7 and 6 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 73576-32:
(7*7)+(6*3)+(5*5)+(4*7)+(3*6)+(2*3)+(1*2)=146
146 % 10 = 6
So 73576-32-6 is a valid CAS Registry Number.
InChI:InChI=1/C7H11N3O/c1-4(2)5-3-6(11)10-7(8)9-5/h3-4H,1-2H3,(H3,8,9,10,11)
73576-32-6Relevant articles and documents
Direct synthesis of 5- and 6-substituted 2-aminopyrimidines as potential non-natural nucleobase analogues
Radhakrishnan,Sharma, Namita,Kundu, Lal Mohan
, p. 15087 - 15090 (2014/04/17)
A series of 2-aminopyrimidine derivatives, substituted at 5- and 6-positions, were synthesized. The reaction was carried out in a single step by treatment of the corresponding β-ketoester or β-aldehydoester with guanidine hydrochloride in the presence of K2CO3, in a microwave-assisted method without the requirement of solvent. A unique 1:1 co-crystal structure was obtained which shows that a 6-phenyl-2- aminopyrimidinone forms a strong nucleobase-pair with cytosine, involving three hydrogen bonds. The base-pair was found to be as strong as that of natural guanine:cytosine (G:C), signifying the potential application of the synthesized derivatives. Additionally, we also report a second co-crystal involving 5-isopropyl-6-methyl-2-aminopyrimidinone and cytosine in a 1:1 ratio, which also shows strong base-pairing properties. the Partner Organisations 2014.
